Evidence map›Paper›PMID 42550371›Full record

ReviewApplied biochemistry and biotechnology2026

Exploring the Biocompatibility and Therapeutic Potential of Graphene Oxide-Based Nanomaterials in Modern Medicine. A Comprehensive Review.

Fozia Aslam, Salamat Ullah Khan Niazi, Muhammad Azam Qamar, Aman Khalid, Muhammad Nouman, Muhammad Zahid, Zulfiqar Ahmad Rehan, Ahmad Farhan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fozia AslamCenter for Biomedical Optics and Photonics (CBOP) & College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, China.
Salamat Ullah Khan NiaziInstitute of Advanced Study in Nuclear Energy & Safety, College of Physics and Optoelectronics Engineering, Shenzhen University, Shenzhen, China.
Muhammad Azam QamarDepartment of Chemistry, School of Science, University of Management and Technology, Lahore, 54700, Pakistan. qamariub@gmail.com.
Aman KhalidDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, Punjab, 38040, Pakistan.
Muhammad NoumanCollege of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, People's Republic of China.
Muhammad ZahidDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, Punjab, 38040, Pakistan.
Zulfiqar Ahmad RehanDepartment of Chemistry, College of Science, Sultan Qaboos University, Al- Khoud-123, Muscat, Oman. z.rehan@squ.edu.om.ORCID http://orcid.org/0000-0001-8508-3156
Ahmad FarhanInternational Center for Interdisciplinary Research in Sciences, The University of Lahore, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene oxide, a 2D nanomaterial, has attracted significant attention for biomedical applications due to its exceptional properties, including tunable surface chemistry, excellent dispersibility, and abundant oxygen-containing functional groups that facilitate facile modification. Recent advancements in the synthesis and functionalization of graphene oxide-based materials have addressed their limitations, such as poor solubility and cytotoxicity, thereby making them safer and more effective for biomedical applications. This paper thoroughly outlines the structural attributes and principal qualities of graphene oxide-based materials, highlighting their mechanical strength, thermal stability, impermeability, electrical conductivity, and biological properties. Emerging developments in graphene oxide-based nanocomposites for fluorescence imaging, magnetic resonance imaging, photoacoustic imaging, Raman spectroscopy imaging, and multifunctional therapeutic platforms are thoroughly examined. Their effectiveness in biomedical scaffolds, wound-healing systems, controlled drug-release platforms, and antimicrobial coatings has been highlighted. Notwithstanding considerable advancements, issues related to cytotoxicity, biodegradability, long-term biosafety, and scalable production continue to impede broad clinical translation. This study offers a cutting-edge overview of graphene oxide-based biomedical systems and outlines promising pathways for advancing safer, more effective, and clinically relevant graphene-based healthcare technologies.

Indexed as

BioimagingBiomedical applicationsDrug delivery systemsGraphene

Identifiers

PMID42550371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.