ArticleJACC. Case reports2026
Hemolysis After Transcatheter Pulmonary Valve Implantation Associated With Residual Shunt Flow.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscatheter pulmonary valve implantation (TPVI) is an established treatment for severe pulmonary regurgitation after repaired tetralogy of Fallot, whereas clinically significant hemolysis is rare. CASE SUMMARY: A 39-year-old man with repaired tetralogy of Fallot developed severe pulmonary regurgitation with progressive right ventricular enlargement. TPVI using a self-expandable Harmony valve was successfully performed. Postprocedural dark-red urine and laboratory findings confirmed hemolysis. Multimodality imaging revealed a coronary artery-right ventricular fistula and residual ventricular septal defect adjacent to the valve. High-velocity shunt flow impinging on the prosthesis was considered the mechanism. Hemolysis resolved with blood pressure control alone. DISCUSSION: Residual shunt lesions adjacent to the right ventricular outflow tract may cause mechanical hemolysis after TPVI by generating localized high-shear stress. This case highlights the importance of comprehensive multimodality imaging before TPVI. TAKE-HOME MESSAGE: Residual shunt flow adjacent to the right ventricular outflow tract may cause mechanical hemolysis after TPVI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.