ArticleInfection and immunity2026
A multivalent subunit vaccine augments pre-existing immunity to protect against T3SS-positive
Debaki R Howlader, Sayan Das, Satabdi Biswas, Zackary K Dietz, Robert K Ernst, William D Picking, Wendy L Picking
Abstract read
In one paragraphArticle in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Debaki R HowladerDepartment of Pathobiology & Integrative Biomedical Sciences and the Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.ORCID 0000-0002-3170-9851 Sayan DasDepartment of Microbial Pathogenesis, University of Maryland, College Park, MD, USA.
Satabdi BiswasDepartment of Pathobiology & Integrative Biomedical Sciences and the Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Zackary K DietzDepartment of Pathobiology & Integrative Biomedical Sciences and the Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
William D PickingDepartment of Pathobiology & Integrative Biomedical Sciences and the Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Wendy L PickingDepartment of Pathobiology & Integrative Biomedical Sciences and the Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.ORCID 0000-0001-7998-0643 Funding
A prophylactic vaccine to prevent colonization by Pseudomonas aeruginosaR01AI169781 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI Wendy L. Picking · 2023 to 2026
$3.1MA vaccine specifically targeting T3SS-negative Pseudomonas aeruginosaR21AI164616 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PICKING, WENDY L. · 2021 to 2022
$423kNIAID NIH HHS HHSN272201800043CNIAID NIH HHS R01 AI169781NIAID NIH HHS R21 AI164616U.S. Department of Health and Human Services HHSN272201800043CU.S. Department of Health and Human Services R01AI169781
6 · The paper itselfAbstract
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Indexed as
Pseudomonas aeruginosaPseudomonas InfectionsPseudomonas VaccinesType III Secretion SystemsAnimalsAntigens, BacterialBacterial ProteinsDisease Models, AnimalFemaleMiceMice, Inbred C57BLProtein Subunit VaccinesVaccines, SubunitAntigens, BacterialBacterial ProteinsProtein Subunit VaccinesPseudomonas VaccinesType III Secretion SystemsVaccines, SubunitL-PaF/E/ME/BECCpre-exposurePseudomonassubunit vaccineT3SSvaccine
Identifiers
PMID42550059
PMCPMC13552108
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