Evidence map›Paper›PMID 42549921›Full record

ArticlemBio2026

Contribution of local

Shingo Bessho, Kaitlyn C M Grando, Sophia Olubajo, Anita T Kowal, Amanda L Miller, Michael H Lee, Vincent Tam, Andres J Klein-Szanto, R Paul Wilson, Stefania Gallucci and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shingo BesshoCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.ORCID 0009-0007-7818-1840
Kaitlyn C M GrandoCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Sophia OlubajoCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Anita T KowalCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Amanda L MillerCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Michael H LeeCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Vincent TamCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Andres J Klein-SzantoHistopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
R Paul WilsonCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Stefania GallucciCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Çağla TükelCenter for Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7073-0226

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Eric Andrew Ross · 1985 to 2026
$138.8M
Role of ZBP1 in pathogenesis of Salmonella biofilmsR01AI171568 · NIAID · RESEARCH INST OF FOX CHASE CAN CTR · PI SIDDHARTH BALACHANDRAN, Cagla Tukel · 2023 to 2026
$3.4M
The role of bacterial amyloid curli in Alzheimer's DiseaseR01AI153325 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI TUKEL, CAGLA · 2020 to 2024
$2.4M
The Role of Eicosanoid-PPAR axis in Exacerbating Post-Influenza Staphylococcus aureus Super-infectionR01AI168550 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI Vincent Tam · 2022 to 2026
$2.0M
Reprogramming of the innate immunometabolism by bacterial biofilmsR21AI180971 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GALLUCCI, STEFANIA · 2024 to 2025
$465k
Epithelial type I interferon signaling in Salmonella typhimurium infectionR21AI137541 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI TUKEL, CAGLA · 2018 to 2019
$436k
Establishing a model of recurrent/chronic urinary tract infection in lupus-prone miceR03AI173522 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GALLUCCI, STEFANIA · 2023 to 2024
$168k
National Institute of Allergy and Infectious Diseases AI153325, AI171568, AI137541National Institute of Allergy and Infectious Diseases AI168550National Institute of Allergy and Infectious Diseases AI173522, AI180971NCI NIH HHS P30 CA006927NIAID NIH HHS R01 AI153325NIAID NIH HHS R01 AI168550NIAID NIH HHS R01 AI171568NIAID NIH HHS R03 AI173522NIAID NIH HHS R21 AI137541NIAID NIH HHS R21 AI180971NIH HHS P30 CA06927
6 · The paper itself

Abstract

IMPORTANCE: Persistent colonization of the gastrointestinal tract by bacterial pathogens can have long-term consequences for host immunity that extend beyond the site of infection. Here, we show that intestinal colonization by

Indexed as

AutoantibodiesAutoimmunityInterferon Type ISalmonella InfectionsSalmonella Infections, AnimalSalmonella typhimuriumAnimalsGerminal CenterMiceMice, Inbred C57BLMice, KnockoutReceptor, Interferon alpha-betaSignal TransductionSpleenAutoantibodiesInterferon Type IReceptor, Interferon alpha-betaamyloidanti-DNAautoantibodyautoimmunitybiofilmscurliSalmonellatype I Interferon

Identifiers

PMID42549921
PMCPMC13556195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.