Evidence map›Paper›PMID 42549779›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2026

What Does α-Syn-SAA-Negative Parkinson's Disease Reveal About the Proposed "Biological Definition" of Parkinson's Disease?

Alberto J Espay, Francisco Cardoso, Steven J Frucht, Alberto Imarisio, Andrew J Lees

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alberto J EspayJames J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.ORCID https://orcid.org/0000-0002-3389-136X
Francisco CardosoMovement Disorders Unit, Neurology Service, Internal Medicine Department, The Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0003-0808-0116
Steven J FruchtThe Marlene and Paolo Fresco Institute for Parkinson's and Movement Disorders, New York University Langone Health, New York, New York, USA.
Alberto ImarisioDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.ORCID https://orcid.org/0000-0002-1206-4170
Andrew J LeesThe National Hospital, Queen Square and Reta Lila Weston Institute for Neurological Studies University College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-2476-4385

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42549779
PMCPMC13518273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.