ArticleCirculation2026
Loss of the Coronary Artery Disease Risk Gene
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In one paragraph
Article in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1citing papers in PubMed
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1 citing paper in PubMed.
Corrections and comments
- Update of
Authors and funding
21 authors.
Amr R SalemDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0001-8269-1420
Ajay KumarDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.
Jaser DojaDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0002-7169-1166
Alshimaa WallyDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.
Chunyu GeDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0009-0006-3011-1563
Sabrina RobichaudDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0001-5766-1094
Orazio J SlivanoDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0009-0007-5884-5822
Susan H GriffinDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0003-1411-153X
Brendan MarshallDepartment of Cellular Biology and Anatomy (B.M., E.P.), Augusta University, GA.
Elizabeth PerryDepartment of Cellular Biology and Anatomy (B.M., E.P.), Augusta University, GA.
J Lee FranklinDepartment of Pathology and Division of Molecular and Cellular Pathology, University of Alabama, Birmingham (J.L.F., V.N.).
Erin H SeeleyDepartment of Core Facilities Management, University of Texas MD Anderson Cancer Center, Houston (E.H.S.).ORCID 0000-0002-8000-5754
Kunzhe DongDepartment of Pharmacology and Toxicology and Immunology Center (K.D.), Augusta University, GA.ORCID 0000-0003-0039-9835
Malgorzata BoczkowskaDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.B., R.D.).ORCID 0000-0003-1677-023X
Gabor CsanyiDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0002-4429-3031
W Bart BryantDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.
Roberto I Vazquez-PadronDeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, FL (R.I.V.-P.).ORCID 0000-0002-9370-276X
Vivek NandaDepartment of Pathology and Division of Molecular and Cellular Pathology, University of Alabama, Birmingham (J.L.F., V.N.).ORCID 0000-0003-1724-7168
Roberto DominguezDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.B., R.D.).ORCID 0000-0003-3186-5229
Xiaochun LongDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0001-9714-0023
Joseph M MianoDepartment of Medicine and Vascular Biology Center (A.R.S., A.K., J.D., A.W., C.G., S.R., O.J.S., S.H.G., G.C., W.B.B., X.L., J.M.M.), Augusta University, GA.ORCID 0000-0001-7522-3207
Funding
Novel Role of MAPK14 in Regulation of VSMC Contractile PhenotypeR01HL122686 · NHLBI · AUGUSTA UNIVERSITY · PI LONG, XIAOCHUN · 2014 to 2022
$4.0MMolecular control of vascular smooth muscle reprogramming in arteriovenous fistula maturationR01DK135284 · NIDDK · AUGUSTA UNIVERSITY · PI Alan Dardik, Xiaochun Long · 2023 to 2026
$2.8MVascular Smooth Muscle Protein Quality Control and Aortic Aneurysm FormationR01HL170024 · NHLBI · AUGUSTA UNIVERSITY · PI Xiaochun Long, Chen Yan · 2023 to 2026
$2.7MFunction and Regulation of TSPAN2 in Vascular DiseaseR01HL139794 · NHLBI · AUGUSTA UNIVERSITY · PI LONG, XIAOCHUN · 2019 to 2023
$2.7MSMC macropinocytosis: a novel target in atherosclerotic vascular diseaseR01HL164792 · NHLBI · AUGUSTA UNIVERSITY · PI Gabor Csanyi · 2023 to 2026
$2.2MThe Role of Vascular Calprotectin in Arteriovenous Fistula MaturationR01DK132888 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Roberto Irenardo Vazquez Padron · 2022 to 2026
$2.1MRegulation and Function of SRF in Vascular PathiobiologyR01HL147476 · NHLBI · UNIVERSITY OF ROCHESTER · PI MIANO, JOSEPH M · 2019 to 2022
$2.1MFunction and Transcriptional Regulation of Leiomodin1R01HL173111 · NHLBI · AUGUSTA UNIVERSITY · PI Joseph M Miano · 2025 to 2026
$1.5MMolecular Mechanisms Controlling Actin Cytoskeleton DynamicsR35GM161161 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ROBERTO DOMINGUEZ · 2026 to 2026
$924kThe Role of Leiomodin1 in Vascular DiseaseR00HL136865 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NANDA, VIVEK · 2020 to 2022
$747kThe Critical Role of Endothelial Inflammation in Arteriovenous Fistula FailureR01DK142422 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Xiaochun Long, Roberto Irenardo Vazquez Padron · 2026 to 2026
$715kThe Role of Leiomodin1 in Vascular DiseaseK99HL136865 · NHLBI · STANFORD UNIVERSITY · PI NANDA, VIVEK · 2018 to 2019
$199kNHLBI NIH HHS K99 HL136865NHLBI NIH HHS R00 HL136865NHLBI NIH HHS R01 HL122686NHLBI NIH HHS R01 HL139794NHLBI NIH HHS R01 HL147476NHLBI NIH HHS R01 HL164792NHLBI NIH HHS R01 HL170024NHLBI NIH HHS R01 HL173111NIDDK NIH HHS R01 DK132888NIDDK NIH HHS R01 DK135284NIDDK NIH HHS R01 DK142422NIGMS NIH HHS R35 GM161161
Abstract
backgroundAtherosclerosis is the primary underlying cause of coronary artery disease.
methodsControl mice (
resultsA lethal neonatal visceral myopathy occurred in
conclusionsUnder atherogenic conditions,
Indexed as
Coronary Artery DiseaseMuscle ProteinsMuscle, Smooth, VascularMyocytes, Smooth MuscleAnimalsCoronary VesselsHumansMaleMiceMice, Inbred C57BLMice, KnockoutMuscle Proteinsatherosclerosiscoronary vesselsmicroscopy, electronsmooth muscle
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.