ReviewCureus2026
Reconsidering the Complex Role of Inflammation in Sudden Infant Death Syndrome.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Within sudden infant death syndrome (SIDS) reside several primary phenomena. These include a state of immune immaturity, susceptibility to infection, and an inflammatory state. Most SIDS risk factors increase the risk of infection (prematurity, lack of breastfeeding, low or absent transplacental antibody, ethnicity, genetics, specific gene polymorphisms associated with susceptibility to infection, poverty, etc.). Most SIDS cases display evidence of an inflammatory state (raised inflammatory markers and inflammatory cytokines). The pattern of inflammation is very similar to that observed following vaccination. The complex relationship between reactogenicity and immunogenicity is examined. Under certain circumstances, reactogenicity can cause immune paralysis and may leave a vulnerable infant open to infection and systemic inflammatory response syndrome, leading to shock. This mechanism is explored in this rapid review in the context of the aetiopathogenesis of SIDS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.