Evidence map›Paper›PMID 42549353›Full record

ArticleFrontiers in toxicology2026

Intestinal toxicity of functionalized polystyrene nanoplastics in NOD2 models of Crohn's disease susceptibility.

Manon Dussol, Sandrine Ménard, Margaux Papin, Maeva Boulée, Vérane Bard, Melvin Airaud, Daphna Fenel, Christine Moriscot, Frédérick Barreau, Marie Carriere

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manon DussolUniv. Grenoble-Alpes, CEA, CNRS, Grenoble-INP, SyMMES-CIBEST, Grenoble, France.
Sandrine MénardIRSD, UMR 1220, INSERM, INRAE, Université de Toulouse, ENVT, Toulouse, France.
Margaux PapinUniv. Grenoble-Alpes, CEA, CNRS, Grenoble-INP, SyMMES-CIBEST, Grenoble, France.
Maeva BouléeUniv. Grenoble-Alpes, CEA, CNRS, Grenoble-INP, SyMMES-CIBEST, Grenoble, France.
Vérane BardUniv. Grenoble-Alpes, CEA, CNRS, Grenoble-INP, SyMMES-CIBEST, Grenoble, France.
Melvin AiraudIRSD, UMR 1220, INSERM, INRAE, Université de Toulouse, ENVT, Toulouse, France.
Daphna FenelIntegrated Structural Biology Grenoble (ISBG), UMS 3518, CNRS, CEA, Université Grenoble Alpes, Grenoble, France.
Christine MoriscotIntegrated Structural Biology Grenoble (ISBG), UMS 3518, CNRS, CEA, Université Grenoble Alpes, Grenoble, France.
Frédérick BarreauIRSD, UMR 1220, INSERM, INRAE, Université de Toulouse, ENVT, Toulouse, France.
Marie CarriereUniv. Grenoble-Alpes, CEA, CNRS, Grenoble-INP, SyMMES-CIBEST, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The daily use of plastic products leads to exposure of populations via ingestion, which may affect intestinal health. While a wealth of studies has documented the impact of micro- and nanoplastics (MNPLs) on models representing healthy human intestine, less is known about their impact on sensitive populations, particularly those at risk of developing inflammatory bowel diseases. This study explored the intestinal response to carboxylated and aminated polystyrene particles (50-500 nm PS-COOH and 50 nm PS-NH

Indexed as

crohn’s diseaseinflammatory bowel diseaseintestinenanoplasticspolystyrenetoxicity

Identifiers

PMID42549353
PMCPMC13432928

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.