Evidence map›Paper›PMID 42549257›Full record

ReviewCureus2026

Anorexia Nervosa, Schizophrenia, and Autism Spectrum Disorder: A Review of the Role of Tanycytes in Individual and Social Behavior.

Prasad Dalvi, Olivia Kelly, Leah Grady, Natalie Carris, Jillian Sullivan, He Liu

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prasad DalviBiology Department, Gannon University, Erie, USA.
Olivia KellyBiology Department, Gannon University, Erie, USA.
Leah GradyBiology Department, Gannon University, Erie, USA.
Natalie CarrisBiology Department, Gannon University, Erie, USA.
Jillian SullivanBiology Department, Gannon University, Erie, USA.
He LiuBiology Department, Gannon University, Erie, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Located along the third ventricle of the hypothalamus, tanycytes are a type of glial cell that are prominent components of metabolic, homeostatic, and immunological signaling and transport. Behavioral deficits observed in disorders such as anorexia nervosa (AN), schizophrenia (SCZ), and autism spectrum disorder (ASD) have been observed and can be linked to the various functions of tanycytes. This review investigates the association between tanycytes and AN, SCZ, and ASD, potentially giving insight into the pathogenesis of these disorders. Specifically, attention is paid to the role of tanycytes in immunological and metabolic pathways, as well as their involvement in the hypothalamic parenchyma via extended processes. Knowledge about the basic molecular and behavioral pathology of AN, SCZ, and ASD may help establish the link between tanycytes and behavior, both on the individual and social level. More mechanistic studies are required, as currently available data are just hypothesis-generating and not mechanistically established.

Indexed as

anorexia nervosa (an)autism spectrum disorder (asd)glial cellsschizophrenia (scz)tanycytes

Identifiers

PMID42549257
PMCPMC13431904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.