ArticleBeyoglu eye journal2026
Structure-Function Relationship in Patients with Glaucoma Suspect: Diagnostic Value and Changes During Follow-up.
Article in Beyoglu eye journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To evaluate anatomical and functional changes during follow-up in eyes with glaucoma suspicion. Methods: A total of 56 eyes of 28 patients (F/M: 21/7) who were included. Detailed ophthalmologic examination, optic coherence tomography (OCT) and visual field (VF -SITA 24-2 and 10-2) were performed at the initial and 12th month examination. Retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses, 24-2 VF global indices (MD, PSD), and 10-2 VF superior and inferior hemi-quadrant mean sensitivities (dB) were recorded. The presence of "cluster defect" was noted in both VFs. Results: The mean age was 56.1±10.8 (34-74) years, mean IOP was 18.2±3.8 mmHg and mean cup/disc ratio (C/D) was 0.4±0.2 at the first visit. There was no significant change in mean IOP and C/D during the follow-up (p=0.655, 0.988, respectively). No significant progression was observed in OCT and VF parameters (p>0.05 for all). At the initial examination, a mild positive correlation was found between total RNFL, GCC and 24-2 MD (r=0.292, 0.316, respectively). At the 12 Conclusion: There's not a single parameter that can be used to differentiate glaucoma suspects from early-stage glaucoma. VF, RNFL and GCC should all be evaluated, and longer follow-ups are necessary.
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