Evidence map›Paper›PMID 42549185›Full record

ArticleQatar medical journal2026

Diagnostic accuracy of CBCT voxel values and calcaneal QUS in detecting low bone mineral density and their association with serum biomarkers.

Neetha Harisha, Shailesh Mane, Amritha C, Rajeshwari G Annigeri

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In one paragraph

Article in Qatar medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Neetha HarishaDepartment of Oral Medicine and Radiology, College of Dental Sciences, Davangere, Karnataka, India.
Shailesh ManeDepartment of Oral Medicine and Radiology, College of Dental Sciences, Davangere, Karnataka, India.
Amritha CDepartment of Oral Medicine and Radiology, College of Dental Sciences, Davangere, Karnataka, India.
Rajeshwari G AnnigeriDepartment of Oral Medicine and Radiology, College of Dental Sciences, Davangere, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Osteoporosis poses significant risks to skeletal health and dental treatment outcomes. This study evaluated the diagnostic potential of cone beam computed tomography (CBCT) voxel values and radiomorphometric analysis in identifying low bone mineral density (BMD), exploring their correlation with calcaneal quantitative ultrasound (QUS) and serum biomarkers. Methods: A cross-sectional study was conducted on 86 participants aged over 40 years. QUS of the calcaneus was utilized to classify subjects into normal or osteopenic/osteoporosis groups. CBCT-derived voxel values (cortical and cancellous) and radiomorphometric indices were recorded alongside serum calcium and 25(OH) vitamin D levels. Statistical analyses included Pearson's/Spearman's correlations and t-tests to compare groups. Results: Participants with normal QUS T-scores exhibited significantly higher CBCT cortical (855.63 ± 71.38) and cancellous (439.90 ± 85.61) voxel values compared to osteoporotic individuals ( Interpretation and Conclusion: CBCT voxel values and CTCI strongly correlate with QUS measurements and vitamin D levels, offering superior diagnostic utility compared to standard morphometric indices. These metrics may serve as effective adjunctive tools for opportunistic osteoporosis screening in dental settings, facilitating early diagnosis and risk management.

Indexed as

Bone mineral densitycomputed tomography cortical indexcone beam computed tomographyosteoporosisquantitative ultrasoundvitamin D

Identifiers

PMID42549185
PMCPMC13430820

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.