ArticleFrontiers in veterinary science2026
Microbiota-associated antioxidant responses to selenium source and probiotic supplementation in beef cattle.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Selenium (Se) and micro-ecological preparations are widely recognized for their roles in enhancing animal health, antioxidant capacity, and production performance. However, their combined effects and underlying mechanisms, particularly involving rumen microbiota, remain poorly understood. This study aimed to investigate the effects of different selenium sources (inorganic vs. organic) combined with micro-ecological probiotic supplementation on growth performance, serum biochemical parameters, antioxidant status, and rumen microbial composition in beef cattle. A total of 24 crossbred Xinjiang Brown steers (average initial body weight: 407.48 ± 36.10 kg; age: 19 months) were assigned to a 2 × 2 factorial design following a 14-day adaptation period and a 37-day feeding trial, with selenium source (sodium selenite vs. yeast selenium) and micro-ecological probiotic supplementation (0 vs. 3%). Growth performance, serum biochemical indices, antioxidant parameters, and rumen microbiota (16S rRNA sequencing) were analyzed. Weighted gene co-expression network analysis (WGCNA) was further employed to explore the associations between microbial modules and host phenotypes. Results showed that selenium source significantly affected feed conversion ratio (FCR), with sodium selenite resulting in improved feed efficiency compared to yeast selenium (
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