Evidence map›Paper›PMID 42549100›Full record

ReviewFrontiers in medicine2026

Applications of dynamic gratings in neuro-ophthalmic disorders.

Xinzuo Zhou, Yuexin Wang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xinzuo ZhouDepartment of Ophthalmology, Peking University Third Hospital, Beijing, China.
Yuexin WangDepartment of Ophthalmology, Peking University Third Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional static vision-based assessment evaluate only stationary, spatial modulated resolution, leaving early and pathway-specific visual impairments undetected. Dynamic gratings are periodically modulating bright-dark stripe stimuli with precisely controllable spatiotemporal parameters that preferentially engage magnocellular and parvocellular visual pathways. Despite this, dynamic grating has not been applied in routine practice due to a lack of standardized protocols, normative databases, and clearly defined clinical indications. This is a narrative review which comprehensively summarizes the motion patterns of dynamic gratings and their clinical utility in neuro-ophthalmic disorders. The five primary motion patterns include phase-alternating oscillation, drift, translation, appearance-disappearance, and rapid serial visual presentation. Through parameter modulation of dynamic gratings, psychophysical and neurophysiological responses are collected, to provide multidimensional evidence for disease mechanism elucidation, diagnosis, and treatment evaluation. These applications are reviewed spanning a spectrum of ophthalmic and neuro-ophthalmic conditions, including glaucoma, amblyopia, strabismus, Graves' ophthalmopathy, diabetic retinopathy, multiple sclerosis, Parkinson's disease, and schizophrenia. The current research provided a foundation for the application of dynamic gratings in clinical ophthalmology. Potential future research should focus on establishing disease-specfic parameter sets and developing an integrated platform to enable standardized clinical implementation.

Indexed as

amblyopiadiabetic retinopathydynamic gratingsglaucomamultiple sclerosisParkinson's diseaseschizophrenia

Identifiers

PMID42549100
PMCPMC13430467

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.