ArticleCHEST pulmonary2024
Lung Volume Changes in Stable Preterm Infants Weaned From Nasal CPAP to High Flow: A Prospective Cohort Study.
Article in CHEST pulmonary, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05237622 (The FUNK-FLOW Study - Functional Residual Capacity During Different Levels of High-flow in Preterm Infants), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The FUNK-FLOW Study - Functional Residual Capacity During Different Levels of High-flow in Preterm Infants
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Weaning preterm infants off nasal CPAP (nCPAP) using nasal high-flow therapy has gained popularity. The effects of such a weaning strategy on lung volumes are unclear. Research Question: How does the transition from nCPAP to high flow and varying flow levels affect lung volumes in stable preterm infants? Study Design and Methods: This was a prospective cohort study in infants 30 to 35 weeks' postmenstrual age. After a baseline period on nCPAP 5 cm H Results: Overall, 8,438 breaths from 19 infants were analyzed. EELV changed significantly during the study ( Interpretation: The results of this study indicate that the transition from nCPAP to high flow is likely to result in a reduced EELV, accompanied by physiological responses in heart rate and oxygenation. Despite a stepwise escalation to preweaning flow levels, we found that only partial recovery of lung volume losses was achievable with high flow. Clinical Trial Registration: ClinicalTrials.gov; No.: NCT05237622; URL: www.clinicaltrials.gov.
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Registered trials
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