Evidence map›Paper›PMID 42548411›Full record

ArticleCHEST pulmonary2026

Current Practices and Preferences Regarding Race and Spirometry Interpretation: A National Survey.

J Henry Brems, Aparna Balasubramanian, Kadija Ferryman, Robert Wharton, Michelle N Eakin, Meredith C McCormack

Abstract read
In one paragraph

Article in CHEST pulmonary, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

J Henry BremsDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Aparna BalasubramanianDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Kadija FerrymanBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD.
Robert WhartonDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Michelle N EakinDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Meredith C McCormackDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Assessing Racial Bias in Pulmonary Medicine from the Interpretation of Pulmonary Function TestsF32HL165771 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BREMS, JOHN HENRY · 2023 to 2023
$79k
NHLBI NIH HHS F32 HL165771NHLBI NIH HHS T32 HL007534
6 · The paper itself

Abstract

Background: The American Thoracic Society recently recommended the use of race-neutral rather than race-specific equations for spirometry interpretation. The uptake of and clinicians' opinions about these practices remain unclear. Research Question: What are clinicians' current practices and opinions around race-specific vs race-neutral reference equations? Study Design and Methods: We conducted a national survey of pulmonologists identified through the American Lung Association and Pulmonary Fibrosis Foundation. Participants completed an electronic survey about their opinions and practices related to race in spirometry reference equations. Descriptive and thematic analyses were conducted. Results: We received and analyzed 66 responses (29% response rate). Respondents had a median age of 48 years (interquartile range, 41-55), and 63 (95%) worked in an academic setting. A total of 34 respondents (54%) reported that their pulmonary function testing laboratory is already using a race-neutral equation. Most (n = 42, 64%) recommended that race-neutral equations should be used for spirometry interpretation, and 6 (9%) recommended race-specific equations alone should be used. When considering alternatives to race-specific equations, the use of Global Lung Function Initiative (GLI)-Global or GLI-Other as a single race-neutral equation was the most preferred alternative (n = 47, 71%). The most cited advantages of race-neutral equations were (1) improving equity, fairness, and bias (48%); and (2) improving accuracy and classification of disease (40%). The most cited disadvantages were (1) misclassification of respiratory disease (25%) and (2) loss of precision of lung function estimates (13%). Interpretation: Our results show that most academic pulmonologists would prefer to use a race-neutral rather than race-specific equation for spirometry interpretation. Although most have already transitioned to a race-neutral approach, significant gaps in implementing GLI-Global remain and indicate needs for ongoing research and education.

Indexed as

PFTspulmonary function testingracereference equationsspirometry

Identifiers

PMID42548411
PMCPMC13418350

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.