Evidence map›Paper›PMID 42548371›Full record

ArticleCHEST pulmonary2025

The Value of a High-Volume Bronchoscopic Lung Volume Reduction Program for Patients With Severe Emphysema.

Amrita D Karambelkar, Juan P Uribe, Alichia Paton, Mihir S Parikh, Jason A Beattie, Chenchen Zhang, Adnan Majid

Abstract read
In one paragraph

Article in CHEST pulmonary, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amrita D KarambelkarDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.
Juan P UribeDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.
Alichia PatonDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.
Mihir S ParikhDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.
Jason A BeattieDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.
Chenchen ZhangDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.
Adnan MajidDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bronchoscopic lung volume reduction (BLVR) has emerged as a promising therapeutic option for patients with COPD. The development of a dedicated BLVR program requires significant resources, both from an interventional pulmonology (IP) team and from the medical center. The financial value of this program is important to assess to develop a feasible and sustainable plan for providing this service in the future. Research Question: Can a BLVR program bring value to a medical center in terms of patient referrals, revenue, and contribution margin? Study Design and Methods: We retrospectively reviewed the charts of patients who were referred for BLVR to the interventional pulmonology clinic at Beth Israel Deaconess Medical Center (BIDMC). Patient demographics were obtained. Outpatient services used to determine candidacy for endobronchial valve placement were analyzed and revenue was estimated. For patients who had valve placement, revenue from the bronchoscopic procedure and subsequent inpatient hospitalization was calculated and the contribution margin of the procedure was estimated. Results: An estimated total of $1 to 1.4 million in revenue was generated in the workup and placement of endobronchial valves for 37 patients. The total revenue for the care of 52 patients deemed not to be candidates for the valve procedure was $144,000 to $170,000. The contribution margin for the procedure was estimated to be 25%. The median length of stay was 3 days. Among all 89 patients referred for BLVR, 26 referrals were made to other specialties at BIDMC during workup. Of these patients, 69.6% were new patients referred to BIDMC for BLVR. Interpretation: In addition to the established therapeutic benefit of BLVR for patients with COPD, a BLVR program in a dedicated, specialized center is economically valuable and sustainable, attracts referrals from other medical centers and health care systems, and generates internal referrals within the medical center.

Indexed as

bronchoscopic lung volume reductionCOPDemphysemaendobronchial valvesinterventional pulmonology

Identifiers

PMID42548371
PMCPMC13418073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.