Evidence map›Paper›PMID 42548198›Full record

ArticleMagnetic resonance in medicine2026

A Deep Nonlinear Subspace Modeling and Reconstruction for Diffusion-Weighted Imaging Using Denoising Auto-Encoder.

Julius Glaser, Zhengguo Tan, Annika Hofmann, Frederik Bernd Laun, Florian Knoll

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Julius GlaserInstitute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0009-0000-9579-1455
Zhengguo TanMichigan Institute for Imaging Technology and Translation (MIITT), Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-4322-5109
Annika HofmannDepartment Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0009-0002-5723-1769
Frederik Bernd LaunInstitute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0000-0002-9269-5609
Florian KnollDepartment Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0000-0001-5357-8656

Funding

Deutsche Forschungsgemeinschaft 440719683Deutsche Forschungsgemeinschaft 500888779Deutsche Forschungsgemeinschaft 512819079Deutsche Forschungsgemeinschaft 513220538Friedrich-Alexander-Universität Erlangen-Nürnberg b143dc
6 · The paper itself

Abstract

purposeTo present a novel, nonlinear subspace modeling and joint k-q-space reconstruction technique for high-resolution, multi-band, multi-shell diffusion-weighted imaging (DWI).

methodsHigh b-value (> 1000 s/mm

resultsComparing the reconstructed data using the proposed method shows improved noise suppression compared to MUSE and more details than LLR-reconstructed images. Specifically, in the higher b-value domain, the reconstruction results show improved detectability of small structures. This bias and precision analysis showed minimal bias introduction, but higher precision with the proposed method.

conclusionOur method combines deep learning, latent signal modeling, joint k-q-space reconstruction, and biophysical simulation for diffusion data and shows strong noise suppression and a high degree of detail in reconstructed diffusion-weighted images.

Indexed as

BrainDiffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedAlgorithmsAutoencoderHumansNonlinear DynamicsSignal-To-Noise Ratiodeep learningdeep nonlinear subspacedenoising auto‐encoderdiffusion weighted magnetic resonance imagingjoint reconstruction

Identifiers

PMID42548198
PMCPMC13527252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.