Evidence map›Paper›PMID 42547805›Full record

ArticleNature neuroscience2026

Developing mouse inhibitory neuron single-cell transcriptomes reveal distinct modes of cell-type diversification.

Minhui Liu, Facundo Ferrero Restelli, Elia Micoli, Giulia Barbiera, Rani Moors, Evelien Nouboers, Malou Reverendo, Jessica Xinyun Du, Hannah Bertels, Dimitris Konstantopoulos and 4 more

Abstract read
In one paragraph

Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Minhui Liu *VIB-KU Leuven Center for Neuroscience, Leuven, Belgium.
Facundo Ferrero Restelli *VIB-KU Leuven Center for Neuroscience, Leuven, Belgium.
Elia Micoli *VIB-KU Leuven Center for Neuroscience, Leuven, Belgium.
Giulia BarbieraGenevia Technologies Oy, Tampere, Finland.
Rani MoorsVIB-KU Leuven Center for Neuroscience, Leuven, Belgium.
Evelien NouboersVIB-KU Leuven Center for Neuroscience, Leuven, Belgium.
Malou ReverendoVIB-KU Leuven Center for Neuroscience, Leuven, Belgium.ORCID http://orcid.org/0009-0008-8412-6757
Jessica Xinyun DuDepartment of Neuroscience, Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5378-4230
Hannah BertelsDepartment of Neurosciences, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.
Dimitris KonstantopoulosGenevia Technologies Oy, Tampere, Finland.
Keimpe WierdaVIB-KU Leuven Center for Neuroscience, Leuven, Belgium.ORCID http://orcid.org/0000-0002-8784-9490
Aya TakeokaRIKEN Center for Brain Science, Saitama, Japan.ORCID http://orcid.org/0000-0003-0322-677X
Giordano LippiDepartment of Neuroscience, Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3911-0525
Lynette LimVIB-KU Leuven Center for Neuroscience, Leuven, Belgium. lynette.lim@kuleuven.be.ORCID http://orcid.org/0000-0003-4179-8373

Funding

Ribo-STAMPEDE: novel tools for molecular profiling of brain cell typesRF1MH126719 · NIMH · SCRIPPS RESEARCH INSTITUTE, THE · PI LIPPI, GIORDANO, YEO, EUGENE WEI-MING · 2022 to 2022
$2.3M
Discovering miRNA-Mediated Mechanisms of Interneuron DevelopmentF31NS118982 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI DU, JESSICA XINYUN · 2021 to 2023
$124k
International Foundation for Research in Paraplegia (Internationale Stiftung für Forschung in Paraplegie) P188NIMH NIH HHS RF1 MH126719NINDS NIH HHS F31 NS118982U.S. Department of Health & Human Services | NIH | Center for Scientific Review (NIH Center for Scientific Review) F31NS118982U.S. Department of Health & Human Services | NIH | Center for Scientific Review (NIH Center for Scientific Review) RF1MH126719Vlaams Instituut voor Biotechnologie (Flanders Institute for Biotechnology) Lim lab
6 · The paper itself

Abstract

The cerebral cortex depends on a diverse repertoire of inhibitory neurons, yet how this diversity emerges during development remains unclear. Rare inhibitory subtypes are often underrepresented in single-cell RNA-sequencing datasets, limiting resolution of their developmental trajectories. Here we developed a computational pipeline to enrich and integrate rare cell types across datasets and applied it to somatostatin-expressing (SST

Indexed as

Cerebral CortexNeural InhibitionNeuronsTranscriptomeAnimalsMiceNeurodevelopmentSingle-Cell AnalysisSingle-Cell Gene Expression AnalysisSomatostatinSomatostatin

Identifiers

PMID42547805
PMCPMC13533839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.