Evidence map›Paper›PMID 42547719›Full record

ArticleOdontology2026

Effectiveness of irrigation systems for removing intracanal medication isthmuses in 3D-printed molars replicas.

J Augusto, A J S Torres-Carrillo, Gustavo Dos Santos Cardoso, P S Gonçalves, I B F Petean, M D Sousa-Neto, J F Mazzi-Chaves, F C Lopes-Olhê

Abstract read
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Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J AugustoDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0003-4801-9504
A J S Torres-CarrilloDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0003-1502-3881
Gustavo Dos Santos CardosoDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0009-0007-2726-219X
P S GonçalvesDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0009-0007-2107-1763
I B F PeteanDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0002-2704-5730
M D Sousa-NetoDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0002-7696-7600
J F Mazzi-ChavesDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0002-9889-1790
F C Lopes-OlhêDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Café s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil. fabiane.lopes@usp.br.ORCID http://orcid.org/0000-0003-4375-3371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effectiveness of four irrigation techniques used during root canal treatment [conventional irrigation (CU), Irriflex (IF), Easy Clean (EC), and passive ultrasonic irrigation (PUI)] in removing calcium hydroxide-based and calcium silicate-based intracanal medications from the isthmus of mesial root canals in 3D-printed mandibular molar replicas. A mandibular molar with presence of an isthmus in the mesial roots and moderate curvature was instrumented with Reciproc R40.06, scanned by Micro Computed Tomography (micro-CT), and used as model to create 64 standardized translucent resin replicas. The mesial roots and isthmus areas were filled with Ultracal XS or Bio-C Temp and scanned again. After 7 days, replicas were reinstrumented and subjected to the irrigation protocols, followed by micro-CT analysis of medication removal. The percentage of remaining intracanal medication volume was analyzed using a t-test. The percentage of medication removed in the isthmus area was also calculated and analyzed using two-way ANOVA (p < 0.05) to evaluate the effects of different factors, followed by Tukey's post hoc test for multiple comparisons. PUI promoted the highest removal of Ultracal XS in percentage (98.2 ± 2.28) (p < 0.05), with no differences among the other techniques. For Bio-C Temp, all protocols performed similarly. PUI showed similar performance for both medications, while the other techniques removed Bio-C Temp more effectively than Ultracal XS.

Indexed as

Intracanal medicationIrrigation techniquesIsthmusMicro-computed tomographyThree-dimensional printing

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.