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ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Preoperative hounsfield unit measurements predict non-infectious complications following posterior spinal instrumentation for traumatic thoracolumbar fractures.

Federico Cardahi, Ali Fazlollahi, Kaveh Mozafari-Lorestani, Paolo Brigato, Ahmed Aoude, Peter Jarzem, Ruldof Reindl, Ouellet Jean, Carlo Santaguida

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Federico CardahiDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada. federico.cardahi@mail.mcgill.ca.
Ali FazlollahiDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.
Kaveh Mozafari-LorestaniDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.
Paolo BrigatoResearch Unit of Orthopedic Surgery, Università Campus Bio-Medico, Rome, Italy.
Ahmed AoudeDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.
Peter JarzemDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.
Ruldof ReindlDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.
Ouellet JeanDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.
Carlo SantaguidaDivision of Orthopedics, Department of Surgery, McGill University, Montreal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical management of traumatic vertebral fractures remains debated. Bone quality influences fixation stability and postoperative complications, yet X-ray absorptiometry (DXA) is rarely available in acute trauma. Computed tomography (CT), routinely obtained during trauma evaluation, enables bone quality assessment. Hounsfield Unit (HU) measurements derived from CT serve as a surrogate for bone mineral density and predictor of complications in degenerative spine surgery; however, their role in traumatic thoracolumbar fracture instrumentation remains unclear. PURPOSE: To evaluate whether preoperative HU measurements predict non-infectious complications following posterior spinal instrumentation for traumatic thoracolumbar fractures. STUDY

designRetrospective cohort study. PATIENT SAMPLE: Patients undergoing spinal instrumentation for traumatic thoracolumbar fractures between 2019 and 2024 at the Montreal General Hospital, Canada. OUTCOME MEASURES: Incidence of non-infectious postoperative complications, including instrumentation failure.

methodsPatients were retrospectively reviewed (mean follow-up 18 months). Data included demographics, preoperative HU values, instrumentation and augmentation techniques, AO fracture classification, levels instrumented, and history of diffuse idiopathic skeletal hyperostosis (DISH) or ankylosing spondylitis (AS). HU values were measured on preoperative CT using three axial slices per vertebral body, averaged across three spine surgeons. Standing radiographs assessed postoperative segmental alignment immediately postoperatively and at one year. Logistic regression identified predictors of non-infectious complications.

resultsAmong 218 patients (141 males, 64.7%; mean age 54.9 years, range 18-92), the most common complications were instrumentation failure (8.7%), infection (3.7%), loss of reduction (3.2%), and proximal junctional kyphosis (1.4%). Each one-unit HU decrease increased complication odds by 2.4% (OR 0.976; 95% CI: 0.959-0.994), corresponding to ~ 21% higher risk per 10-HU decreases from the cohort mean of 177.56 HU (SD 70.07) at the vertebral level above the fracture.

conclusionsLower preoperative HU values are associated with increased risk of non-infectious complications following instrumentation for traumatic thoracolumbar fractures. HU measurements may aid surgical planning and risk stratification and should be interpreted alongside other clinical and fracture-specific factors.

Indexed as

Bone mineral densityComplicationsFractureHounsfield unitLumbarOpen approachPercutaneousReduction lossThoracicTraumatic

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.