Evidence map›Paper›PMID 42547524›Full record

ArticleBritish dental journal2026

An important change in infective endocarditis prevention guidance.

Martin H Thornhill, Charlotte Eckhardt, Bernard Prendergast, Mark Dayer, Greg Hutton, Larry M Baddour

Abstract read
In one paragraph

Article in British dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martin H ThornhillSchool of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom. M.Thornhill@Sheffield.ac.uk.
Charlotte EckhardtMaxillofacial Department, Morriston Hospital, Swansea Bay University Health Board, United Kingdom.
Bernard PrendergastCleveland Clinic, London, United Kingdom.
Mark DayerCardiovascular Research Institute, Mater Private Network, Dublin, Ireland; Faculty of Health, University of Plymouth, Plymouth, United Kingdom.
Greg HuttonInfective Endocarditis Patient, Patient Advocate, United Kingdom.
Larry M BaddourDivision of Public Health, Infectious Diseases, and Occupational Health, Departments of Medicine and Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent changes to the National Institute for Health and Care Excellence (NICE) guidelines combined with an update to the implementation advice from the Scottish Dental Clinical Effectiveness Programme (SDCEP) have resulted in significant changes to the advice given to dentists concerning the prevention of infective endocarditis (IE). In contrast to a previous NICE recommendation against the use of AP for IE prevention, dentists are now recommended to offer antibiotic prophylaxis (AP) to all individuals at high-risk of IE before extractions or oral surgery procedures, and to consider AP for high-risk individuals undergoing any other at-risk dental procedures that involve manipulation of the gingival or periapical region of the teeth.Most UK cardiologists, cardiothoracic surgeons and infectious disease specialists (alongside many National Health Service trusts, several of which incorporate dental schools and hospitals) follow the European Society for Cardiology (ESC) guidelines. Awareness of the changes made by NICE and SDCEP, and the similarities and differences between their updated recommendations and the ESC guidelines, is therefore essential.

Indexed as

Antibiotic ProphylaxisEndocarditisEndocarditis, BacterialPractice Guidelines as TopicHumansOral Surgical ProceduresUnited Kingdom

Identifiers

PMID42547524
PMCPMC13524779

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.