Evidence map›Paper›PMID 42547466›Full record

ArticleAllergy, asthma & immunology research2026

Associations Between Serum Resolvin D1 Levels and Food Allergy Persistence in Children.

Mireu Park, Haerin Jang, Sumin Lee, Eun Gyul Kim, Mi Na Kim, Hamin Kim, Soo Yeon Kim, Lark Kyun Kim, Jong Deok Kim, Yong Ju Lee and 4 more

Abstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predictive Biomarker for Persistent Food Allergy in Children.Allergy, asthma & immunology research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mireu ParkDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4342-6143
Haerin JangDepartment of Human Genetics, Wellcome Sanger Institute, Hinxton, UK.ORCID https://orcid.org/0000-0003-3237-2813
Sumin LeeDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0003-4663-9133
Eun Gyul KimDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2546-9919
Mi Na KimDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1675-0688
Hamin KimDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0601-7300
Soo Yeon KimDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4965-6193
Lark Kyun KimDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5983-4470
Jong Deok KimDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4266-5655
Yong Ju LeeDepartment of Pediatrics, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.ORCID https://orcid.org/0000-0002-0796-2558
Min Jung KimDepartment of Pediatrics, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.ORCID https://orcid.org/0000-0002-5634-9709
Yoon Hee KimDepartment of Pediatrics, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2149-8501
Myung Hyun SohnDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2478-487X
Kyung Won KimDepartment of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4529-6135

Funding

National Research Foundation of Korea 2022R1A2C1010462National Research Foundation of Korea RS-2024-00408822
6 · The paper itself

Abstract

purposeThe pathophysiology and natural course of childhood food allergies (FAs) remains largely elusive. Recent findings have implicated resolvins, omega-3 metabolites, in the pathogenesis and resolution of FAs, highlighting their potential clinical significance. This investigation aimed to elucidate the clinical implications of resolvins in the manifestation and resolution of childhood FAs.

methodsSerum samples were collected from a cohort of children diagnosed with FA and healthy controls upon their first visit to the Severance Children's Hospital (Seoul, Korea). FA persistence was assessed for each patient based on follow-up records. Resolvin D1 (RvD1) levels were measured and their correlation with total immunoglobulin E (IgE) and allergen-specific IgE levels were evaluated.

resultsThis study included 278 children (mean age 3.28 ± 3.17 years; 62% male), consisting of 92 children with resolved FA (resolved FA group), 113 children with persistent FA (persistent FA group), and 73 children (control group). RvD1 levels were significantly higher in children with FA than in controls (

conclusionsOur findings suggest that RvD1 is a candidate metabolite associated with the persistence of childhood FA, across various food allergens and may provide complementary information to existing clinical features.

Indexed as

biomarkerschildFood hypersensitivityresolvin D1

Identifiers

PMID42547466
PMCPMC13441552

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.