Evidence map›Paper›PMID 42547243›Full record

ArticleBMJ open2026

Magnitude of human papillomavirus vaccination uptake and its determinants among adolescent girls in Lesotho: a cross-sectional study.

Tsion Mulat Tebeje, Kassahun Animut Metkie, Yordanos Sisay Asgedom, Amanuel Yosef Gebrekidan, Seblewongel Gebretsadik Sertsewold, Ermias Bekele Enyew, Mesfin Abebe

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Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Tsion Mulat TebejeSchool of Public Health, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia yemarina12@gmail.com.ORCID 0000-0002-2911-2095
Kassahun Animut MetkieDepartment of Statistics, College of Natural and Computational Science, Dilla University, Dilla, Ethiopia.ORCID 0000-0003-0744-9022
Yordanos Sisay AsgedomDepartment of Epidemiology and Biostatistics, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, SNNPR, Ethiopia.ORCID 0000-0001-5226-1200
Amanuel Yosef GebrekidanSchool of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Sodo, Ethiopia.
Seblewongel Gebretsadik SertsewoldAsrat Woldeyes Health Science campus, Debrebirhan University, Debrebirhan, Ethiopia.ORCID 0009-0005-3939-0135
Ermias Bekele EnyewDepartment of Health Informatics, School of Public Health, College of Medicine and Health Science, Wollo University, Dessie, Amhara, Ethiopia.ORCID 0000-0002-9310-2481
Mesfin AbebeDepartment of Midwifery, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.ORCID 0000-0002-9340-0091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo eliminate cervical cancer as a public health problem, the WHO recommends that human papillomavirus (HPV) vaccines should be included in national immunisation programmes and should reach 90% of all girls by age 15 as primary prevention. Lesotho reintroduced the national HPV vaccine programme in 2022.

objectiveTo investigate the prevalence and associated factors of HPV vaccination uptake among adolescent girls in Lesotho.

designA population-based cross-sectional study design.

settingLesotho.

participantsGirls aged 15-17. PRIMARY AND SECONDARY OUTCOME MEASURES: A multilevel Poisson regression model with robust variance was applied to identify factors associated with HPV vaccination uptake. An adjusted prevalence ratio with a 95% CI was reported.

resultsThe uptake of HPV vaccination among adolescent girls in Lesotho was 52.15% (95% CI 48.43 to 55.84). Girls aged 16 and 17 and those residing in the Maseru district were significantly associated with a lower proportion of HPV vaccination uptake. While, ever heard of cervical cancer and ever heard of sexually transmitted infections (STIs) were found to be linked with a higher proportion of HPV vaccination uptake.

conclusionHPV vaccination uptake among adolescent girls in Lesotho was far behind the WHO 2030 target. Raising awareness about cervical cancer and HPV vaccination via targeted education is vital. A comprehensive sexual health education programme that includes information on STIs and HPV can improve vaccination uptake, especially in districts with low uptake.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsVaccinationAdolescentCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHuman Papillomavirus VirusesHumansImmunization ProgramsLesothoPapillomavirus Vaccinesadolescent girlsdemographic and health surveyHuman papillomavirus vaccinationLesotho

Identifiers

PMID42547243
PMCPMC13436095

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