Evidence map›Paper›PMID 42545801›Full record

ArticleAnnals of medicine2026

The audiologic characteristics for children with cochlear nerve deficiency and the association with the outcome of cochlear implant surgery.

Ruirui Guan, Wenyun Luo, Wan Zhao, Jingwu Sun, Jiaqiang Sun, Chunyan Li, Xiaotao Guo

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Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ruirui GuanDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Wenyun LuoDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Wan ZhaoDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Jingwu SunDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Jiaqiang SunDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Chunyan LiDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Xiaotao GuoDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to investigate the audiological characteristics of children with cochlear nerve deficiency (CND) and their correlation with cochlear implantation (CI) prognosis.

methodsThe records of 48 patients (24 with bilateral CND and 24 with no inner ear malformations (IEMs)) who underwent unilateral CI were reviewed. Preoperative audiometric, postoperative electrical stimulation auditory brainstem response (EABR), and auditory performance measures were also assessed.

resultsCND patients demonstrated a significantly higher positive wave detection rate (41.67%) compared with controls (0%,

conclusionsThe presence of a distinctive positive waveform in auditory brainstem response (ABR) testing may indicate preserved residual auditory pathway integrity in CND patients. This characteristic may serve as a prognostic indicator for CI outcomes, warranting further investigation in larger, longitudinal cohorts.

Indexed as

Cochlear ImplantationCochlear ImplantsCochlear NerveVestibulocochlear Nerve DiseasesAudiometryAuditory AcuityChildChild, PreschoolEvoked Potentials, Auditory, Brain StemFemaleHumansInfantMalePrognosisRetrospective StudiesTreatment Outcomeauditory brainstem responsecochlear implantationCochlear nerve deficiencyelectrically evoked auditory brainstem responsepositive wave

Identifiers

PMID42545801
PMCPMC13435270

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