Observational studyIndian journal of ophthalmology2026
Surgical interventions in herpes simplex virus keratitis: Outcomes in a large cohort.
Observational study in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHerpes simplex virus (HSV) keratitis is a significant cause of infectious corneal morbidity worldwide. Severe cases may require surgical intervention when medical therapy fails. This study evaluates surgical outcomes in managing advanced HSV keratitis.
methodsThis was a retrospective observational cohort study conducted at a single tertiary care center. The objective was to assess the effectiveness of surgical interventions in stabilizing the ocular surface and improving visual acuity (VA) in patients with HSV keratitis. A retrospective analysis was performed on 377 patients who underwent surgical intervention for HSV keratitis between January 2020 and December 2023. Surgical indications included corneal perforations, persistent epithelial defects, neurotrophic keratitis, and visual rehabilitation. The primary outcomes were ocular surface stability and VA improvement.
resultsPrimary surgeries such as tissue adhesive with bandage contact lens, tarsorrhaphy, and penetrating keratoplasty achieved ocular surface stability in 74.3% of patients. A second surgical intervention was required in 57.02% of cases. VA improved significantly, with 8.22% achieving 6/18 or better at final follow-up.
conclusionMinimally invasive surgical techniques play a critical role in stabilizing the ocular surface in severe HSV keratitis. A stepwise, tailored surgical approach allows optimization of outcomes while deferring high-risk emergency keratoplasty.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.