Evidence map›Paper›PMID 42545601›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Unsuccessful percutaneous left atrial appendage occlusion: A single center perspective.

Adnan Ahmed, Rachad Ghazal, Aashish Katapadi, Danish Bawa, Vasvi Singh, Nicholas Pham, Naga Venkata Pothineni, Douglas Darden, Rakesh Gopinathannair, Dhanunjaya Lakkireddy and 1 more

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adnan AhmedDepartment of Cardiology, HCA Midwest, Overland Park, KS, USA.
Rachad GhazalDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Aashish KatapadiDepartment of Cardiology, HCA Midwest, Overland Park, KS, USA.
Danish BawaDepartment of Cardiology, HCA Midwest, Overland Park, KS, USA.
Vasvi SinghDepartment of Cardiology, HCA Midwest, Overland Park, KS, USA.
Nicholas PhamA.T. Still, University of Health Sciences, Kirksville, MO, USA.
Naga Venkata PothineniKansas City Heart Rhythm Institute, HCA Midwest, 5100 W. 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Douglas DardenKansas City Heart Rhythm Institute, HCA Midwest, 5100 W. 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Rakesh GopinathannairKansas City Heart Rhythm Institute, HCA Midwest, 5100 W. 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Dhanunjaya LakkireddyKansas City Heart Rhythm Institute, HCA Midwest, 5100 W. 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Rajesh KabraKansas City Heart Rhythm Institute, HCA Midwest, 5100 W. 110th Street, Suite 200, Overland Park, KS, 66211, USA. rajesh.kabra@hcahealthcare.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpicardial and endocardial left atrial appendage occlusion (LAAO) is commonly performed for stroke prevention for atrial fibrillation (AF) patients at increased risk for stroke who cannot tolerate long-term oral anticoagulation. However, there is limited data on the outcomes of unsuccessful LAAO procedures. This study aims to assess the incidence and outcomes of unsuccessful LAAO procedures.

methodsA retrospective analysis was performed on patients undergoing LAAO at our institution from 2020 to 2023. The primary endpoint was a failure to deploy the LAAO device, which was defined as unsuccessful device implantation (UDI).

resultsA total of 411 patients underwent LAAO (Lariat = 6.8%, Amulet = 56.4%, and Watchman FLX/FLX Pro = 36.7%). UDI was observed in 4.9% (n = 20) of procedures. The cohort's mean age was 77.1 ± 10 years, and 45% were males. The mean CHA

conclusionLAAO demonstrates a low failure rate and is generally safe. LAA morphology significantly influences the procedure's success, with AtriClip surgical exclusion often serving as an option after UDI.

Indexed as

AnticoagulationAtrial fibrillationImplantation failureLeft atrial appendage occlusionPericardial complicationsStroke preventionUnsuccessful device implantation

Identifiers

PMID42545601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.