Evidence map›Paper›PMID 42545249›Full record

ArticleLa Medicina del lavoro2026

Interstitial Lung Disease in a Dental Technician Diagnosed Through an Integrated Multidisciplinary Approach.

Giacomo Giulianelli, Giuseppe Maggioni, Matteo Daverio, Roberta Polverosi, Mila Della Barbera, Paola Mason, Paolo Spagnolo, Cristina Basso, Fiorella Calabrese, Stefania Rizzo and 1 more

Abstract readCase Reports
In one paragraph

Article in La Medicina del lavoro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giacomo GiulianelliRespiratory Disease Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Giuseppe MaggioniPathological Anatomy Section; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy. PhD Program in Translational Specialistic Medicine "G.B. Morgagni", Curriculum "Thoracic and Pulmonary Sciences"; University of Padua, Italy.
Matteo DaverioRespiratory Disease Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy. PhD Program in Translational Specialistic Medicine "G.B. Morgagni", Curriculum "Thoracic and Pulmonary Sciences"; University of Padua, Italy.
Roberta PolverosiAntoniano Diagnostic Institute, Affidea; Padua, Italy.
Mila Della BarberaCardiovascular Pathology Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Paola MasonOccupational Medicine Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Paolo SpagnoloRespiratory Disease Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Cristina BassoCardiovascular Pathology Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Fiorella CalabresePathological Anatomy Section; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Stefania RizzoCardiovascular Pathology Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Elisabetta BalestroRespiratory Disease Unit; University Hospital, Padua, Italy. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence from the literature indicates that workers in the dental care sector are routinely exposed to hazardous airborne agents, particularly mineral and metal dusts. This occupational risk is further amplified in settings with inadequate ventilation and insufficient use of personal protective equipment. We discuss the case of a dental technician with a significant history of occupational exposure who presented to our clinic with exertional dyspnea. High-resolution computed tomography revealed fibrosing nonspecific interstitial pneumonia associated with emphysema, and spirometry showed a severe reduction in carbon monoxide diffusion capacity. After a multidisciplinary evaluation, we performed bronchoscopy with bronchoalveolar lavage (BAL), which revealed an abundance of macrophages. Scanning electron microscopy with energy-dispersive spectrometry of the BAL detected silicon oxide, calcium, iron, and traces of metals typical of dental alloys (titanium, aluminum), as well as rare earth elements and toxic pollutants. These findings supported the diagnosis of interstitial lung disease due to long-term occupational exposure in dental laboratories, enabling a minimally invasive diagnostic approach. This strategy obviated the need for transbronchial biopsy, thereby avoiding a procedure associated with a high risk of pneumothorax in this patient.

Indexed as

Dental TechniciansLung Diseases, InterstitialOccupational DiseasesOccupational ExposureAgedBronchoalveolar Lavage FluidBronchoscopyHumansMalePatient Care Team

Identifiers

PMID42545249
PMCPMC13510299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.