ArticleLa Medicina del lavoro2026
A Portable Heat-Exchange-Based System for Assessing Digital Vascular Response to Cold.
Article in La Medicina del lavoro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDigital vascular assessment is relevant in occupational medicine, but current measurement methods may be complex and poorly portable.
objectiveTo validate a portable heat-exchange-based system for assessing cold-induced digital vascular response, using strain-gauge plethysmography as the reference method.
methodsTwenty healthy volunteers, 10 males and 10 females, underwent five subsequent sessions. Finger blood flow (FBF) was assessed by strain-gauge plethysmography, while simultaneously, fingertip thermal power (TP) was recorded with a portable thermoflowmeter. FBF was measured at baseline, while both FBF and TP were measured during application of 1-N contact force alone and during 1-N force combined with local cooling at 10 °C. The relationship between TP and FBF, after adjustment for covariates (age, sex, body mass index (BMI), and room temperature), was evaluated in the cooled condition using a linear mixed model including fixed and random effects.
resultsLocal cooling induced a significant vascular response, with FBF decreasing from 1.23 to 0.98 ml/100 ml/s (p<0.0001). In the cooled-condition model, TP was significantly associated with FBF, with each 1 ml/100ml/s increase in FBF corresponding to a 39.6 mW increase in TP (p<0.0001). Under cooling, TP showed lower within-subject variability than FBF (wsCV ≈0.19 vs ≈0.64). BMI was positively associated with TP (4.40 mW per kg/m², p=0.007), whereas age and sex were not significant predictors.
conclusionsThese findings support the interpretation of TP as a perfusion-related thermal descriptor with potential applicability in occupational health surveillance. Further validation in subjects with digital vascular disorders is needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.