Evidence map›Paper›PMID 42544850›Full record

ArticlePediatrics international : official journal of the Japan Pediatric Society

Is Procedural Intravenous Anesthesia Safe for Children? An Analysis of Nationwide Accident Registries in Japan.

Megumi Matsumoto, Eisuke Inage, Shun Toriumi, Akifumi Endo, Yosuke Nakabayashi, Susumu Yokoya, Itaru Iwama, Yasuyuki Suzuki, Shoichi Oyama, Nobuaki Michihata and 4 more

Abstract read
In one paragraph

Article in Pediatrics international : official journal of the Japan Pediatric Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Is Pediatric Procedural Sedation Safe? A Nationwide Wake-Up Call.Pediatrics international : official journal of the Japan Pediatric Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Megumi MatsumotoDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0009-0005-8503-5759
Eisuke InageDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9442-3666
Shun ToriumiDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Akifumi EndoDepartment of Pediatrics, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8788-4042
Yosuke NakabayashiAdvanced Medical Emergency Department & Critical Care Center, Japanese Red Cross Maebashi Hospital, Maebashi, Japan.ORCID https://orcid.org/0009-0001-6657-7342
Susumu YokoyaThyroid and Endocrine Center, Fukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan.ORCID https://orcid.org/0000-0002-5599-0481
Itaru IwamaDevision of Gastroenterology and Hepatology, Saitama Children's Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0001-8677-8195
Yasuyuki SuzukiDepartment of Anesthesiology, Tokyo Women's Medical University, Tokyo, Japan.
Shoichi OyamaDepartment of Pediatrics, Saiseikai Kawaguchi General Hospital, Saitama, Japan.
Nobuaki MichihataCancer Prevention Center, Chiba Cancer Center Research Institute, Chiba, Japan.ORCID https://orcid.org/0000-0003-3091-114X
Takahiro KudoDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-4708-8049
Yoshikazu OhtsukaDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8109-084X
Toshiaki ShimizuDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hiromichi ShojiDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2532-8910

Funding

JSPS KAKENHI JP 60749951
6 · The paper itself

Abstract

backgroundAlthough pediatric intravenous anesthesia is widely employed outside operating rooms, it poses risks for serious complications such as airway obstruction and apnea. In Japan, the actual numbers and trends of medical accidents associated with pediatric intravenous anesthesia remain unclear, and the safety of procedural intravenous anesthesia in children has not been sufficiently investigated.

methodsWe extracted accident reports on pediatric intravenous anesthesia for medical procedures from a nationwide, anonymized Japanese accident registry database over 13 years. The reports were analyzed to describe the clinical characteristics of the reported severe adverse events.

resultsA total of 79 accident reports related to intravenous anesthesia were registered, accounting for 0.017% of the total number of intravenous anesthesia procedures. Among these, 70 (88.6%) accident cases occurred in children aged 0-9 years and 9 (11.8%) in patients older than 10 years. Four cases resulted in death and eight in cardiopulmonary arrest, all involving serious underlying medical conditions and occurring during prolonged and highly invasive procedures. When categorized by age, six cases (75.0%) involved children aged 0-9 years and 2 (25.0%) involved patients older than 10 years. The most common underlying disease categories were cardiac disease (n = 7) and the most frequent procedures were cardiac catheterization (n = 5). The number of physicians exclusively assigned to anesthesia induction and monitoring using capnometers was not reported.

conclusionsThis nationwide registry analysis characterizes severe pediatric intravenous anesthesia-related adverse events in Japan and highlights the importance of risk stratification and specialist involvement in high-risk cases.

Indexed as

Anesthesia, IntravenousAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornJapanMalePediatric AnesthesiaRegistriesaccidentsapneacardiac arrestdeep sedationintravenous anesthesia

Identifiers

PMID42544850
PMCPMC13430577

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.