Evidence map›Paper›PMID 42544777›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2026

Identification and Discrimination of Sulfated and Unsulfated Gut-Hormone Biomarkers in Human Serum by Nanopore.

Luca Iesu, Laurent Bacri, Juan Pelta, Benjamin Cressiot

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luca IesuCNRS, LAMBE, Université Paris-Saclay, Univ. d'Évry, CY Cergy Paris Université, Cergy, France.ORCID https://orcid.org/0000-0002-4055-7909
Laurent BacriCNRS, LAMBE, Université Paris-Saclay, Univ. d'Évry, CY Cergy Paris Université, Évry-Courcouronnes, France.ORCID https://orcid.org/0000-0002-1763-2456
Juan PeltaCNRS, LAMBE, Université Paris-Saclay, Univ. d'Évry, CY Cergy Paris Université, Évry-Courcouronnes, France.ORCID https://orcid.org/0000-0002-1896-4137
Benjamin CressiotCNRS, LAMBE, Université Paris-Saclay, Univ. d'Évry, CY Cergy Paris Université, Cergy, France.ORCID https://orcid.org/0000-0001-9319-3152

Funding

French Research Agency ANR-23-CE44-0013
6 · The paper itself

Abstract

Cholecystokinin-8, an octapeptide, is a gut hormone mainly involved in the digestive process and neuromodulation. Over the last four decades, its biological functions have been elucidated and shown to be critically modulated by tyrosine sulfation. Recently, this octapeptide has been identified as a potential biomarker in several tumours. Regrettably, there are no clinical or analytical methods capable of distinguishing between the unsulfated (CCK-8) and sulfated (SO

Indexed as

BiomarkersCholecystokininGastrointestinal HormonesNanoporesSulfatesHumansBiomarkersCholecystokininGastrointestinal HormonesSulfatesbiofluidsgastric cancer biomarkersnanoporespeptidesPTMs

Identifiers

PMID42544777
PMCPMC13630408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.