Evidence map›Paper›PMID 42544182›Full record

ReviewBurns & trauma2026

Application and prospects of organoid-on-a-chip in research on the intestinal mucosal barrier.

Kun Qian, Yiwen Wang, Ran Li, Mengmeng Zhuang, Zhengnan Zhao, Chao Meng, Jiayun Zhou, Wensheng Wang, Yong Sun

Abstract readReview
In one paragraph

Review in Burns & trauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kun QianDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.ORCID https://orcid.org/0009-0003-9247-2901
Yiwen WangDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Ran LiDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Mengmeng ZhuangDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Zhengnan ZhaoDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Chao MengDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Jiayun ZhouDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Wensheng WangDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.
Yong SunDepartment of Burn Surgery, the Affiliated Huaihai Hospital of Xuzhou Medical University, No. 226 Tongshan Road, Yunlong District, Xuzhou, Jiangsu Province 221004, China.ORCID https://orcid.org/0000-0001-5720-2779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integrity of the intestinal mucosal barrier is essential for maintaining normal gut physiology, and its disruption is associated with a wide range of conditions, including trauma- and burn-related intestinal injury, which remain difficult to manage clinically. Intestinal organoid-on-a-chip systems have emerged as advanced

Indexed as

Gut–organ-axis-on-a-chipIntestinal barrier repairIntestinal injuryIntestinal mucosal barrierIntestinal organoidsOrganoid-on-a-chipOrgan-on-a-chip

Identifiers

PMID42544182
PMCPMC13429053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.