Evidence map›Paper›PMID 42544012›Full record

ArticlePediatric pulmonology2026

Acute Supraglottitis in Pediatric Patients-An Emerging Disease?

Avital Weiss Shachar, Rotem Pistiner Hanit, Doron Mulla, Elhanan Nahum, Eytan Kaplan, Avichai Weissbach, Haim Ben Zvi, Oded Scheuerman, Gili Kadmon

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Avital Weiss ShacharGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Rotem Pistiner HanitGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Doron MullaGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Elhanan NahumGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Eytan KaplanGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Avichai WeissbachGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Haim Ben ZviGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Oded ScheuermanGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.
Gili KadmonGray Faculty of Medicine and Health Science, Tel Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSupraglottitis is an acute inflammation of the epiglottis and entire supraglottic structures, and a potential cause of upper airway obstruction in children. However, data on pediatric supraglottitis remain very limited. This study aims to describe the epidemiological, clinical, laboratory, and microbiological characteristics of pediatric supraglottitis, with particular emphasis on identifying its various etiologies. STUDY

designWe conducted a retrospective review of medical records of children admitted to the pediatric intensive care unit of a tertiary pediatric hospital with a diagnosis of supraglottitis, between 2004 and 2024. Patients were subsequently categorized into two groups: with adenovirus-associated supraglottitis and supraglottitis attributable to other etiologies.

resultsA total of 32 children with supraglottitis were included. The incidence increased by 330% between the first and second decades of the study. The most common presenting features were fever, stridor, and dyspnea. Invasive mechanical ventilation was required for 53% of patients, while 9% received noninvasive ventilation. A viral etiology was identified in 19/30 (63%) patients, with adenovirus being the most frequently detected pathogen (10 of 19 cases). Bacterial pathogens were isolated from sputum cultures in 16/17 patients, most commonly Streptococcus group A. Children with adenovirus-associated supraglottitis had significantly higher fever and C-reactive protein levels.

conclusionsIn this pediatric supraglottitis cohort, incidence increased over time. Respiratory viral infections were evident in most cases, with adenovirus identified as the most common pathogen.

Indexed as

SupraglottitisAcute DiseaseAdenoviridae InfectionsAirway ObstructionChildChild, PreschoolDyspneaFemaleFeverHumansIncidenceInfantMaleRespiration, ArtificialRespiratory SoundsRetrospective Studiesadenovirusairway obstructionepiglottitisetiologystridorviral infection

Identifiers

PMID42544012
PMCPMC13430291

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.