ArticleNephrology (Carlton, Vic.)2026
Persistent Haematuria Is Associated With Reduced Kidney Survival in Primary Podocytopathies.
Article in Nephrology (Carlton, Vic.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimHaematuria is frequently present in podocytopathies, but its significance and prognostic value are not well described. This study aimed to determine the prevalence and association between persistent haematuria and kidney survival in patients with membranous nephropathy (MN), minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS).
methodsWe conducted a retrospective cohort study of 236 adults with biopsy-proven primary podocytopathies. Persistent haematuria was defined as ≥ 5 red blood cells per high-power field in ≥ 3 consecutive urine specimens within 3 months post-biopsy. The primary outcome was end-stage kidney disease (ESKD) requiring chronic renal replacement therapy. Kaplan-Meier analysis and Cox proportional hazards regression were performed.
resultsAmong 236 participants (114 MN, 76 MCD, 46 FSGS), 73 (31%) had persistent haematuria. Participants with haematuria had higher proteinuria (5.3 vs. 3.2 g/g, p = 0.01) and were more likely to have hypertension (55% vs. 36%, p = 0.007). During a median follow-up of 96 months, 38 patients (16%) reached ESKD. ESKD incidence was significantly higher in patients with persistent haematuria (32% vs. 9%, p < 0.001). After adjusting for diagnosis, eGFR, proteinuria, Charlson comorbidity score and histological chronicity score, persistent haematuria remained independently associated with ESKD (hazard ratio: 3.55; 95% CI: 1.78-7.05; p < 0.001).
conclusionPersistent haematuria is prevalent among patients with podocytopathies and is significantly and independently associated with ESKD. Urinalysis, including microscopic haematuria assessment, is widely available and inexpensive, providing a valuable data point to help formulate patient prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.