Transarterial Embolization Versus Manipulation Under Anesthesia and Arthroscopic Capsular Release for Refractory Adhesive Capsulitis-A Cost-Effectiveness Analysis.

Kameel Khabaz, Rashed Alananzeh, Layth Alkhani, Sammy Allaw, Xiao Wu, Qian Yu, Mikin Patel, Osman Ahmed

Abstract readSystematic ReviewComparative StudyMeta-Analysis

In one paragraph

Synthesis in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kameel KhabazDavid Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA. khabazkameel@gmail.com.ORCID http://orcid.org/0000-0002-3164-6133

Rashed AlananzehDavid Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.

Layth AlkhaniJoint & Vascular Institute, Libertyville, IL, 60048, USA.

Sammy AllawDepartment of Radiology, University of Chicago, Chicago, IL, 60637, USA.

Xiao WuDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94143, USA.

Qian YuDepartment of Radiology, University of Chicago, Chicago, IL, 60637, USA.

Mikin PatelJoint & Vascular Institute, Libertyville, IL, 60048, USA.

Osman AhmedJoint & Vascular Institute, Libertyville, IL, 60048, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared the cost-effectiveness of transarterial embolization (TAE), manipulation under anesthesia (MUA), and arthroscopic capsular release (ACR) for refractory primary adhesive capsulitis. A systematic review with single-arm meta-analyses informed a three-state Markov model over a 36-month horizon. Clinical success, defined as mild pain at 3 months, was highest for TAE (73.3%), followed by ACR (61.4%) and MUA (55.5%). At a $100,000 per quality-adjusted life-year (QALY) threshold, TAE was the optimal strategy (incremental cost-effectiveness ratio vs. ACR: $77,807/QALY). When success was defined by range-of-motion recovery, MUA and ACR yielded more QALYs at lower cost. Based on indirect comparisons, these findings suggest TAE may be a cost-effective option for pain-predominant adhesive capsulitis, while MUA and ACR may be preferred when mechanical restriction is the primary target.

Indexed as

AnesthesiaArthroscopyBursitisEmbolization, TherapeuticJoint Capsule ReleaseCost-Benefit AnalysisCost-Effectiveness AnalysisHumansAdhesive capsulitisCost-effectiveness analysisEmbolizationHealth system economicsMeta-analysisMusculoskeletal interventionsSystematic review

Identifiers

PMID42543403

DOI10.1007/s00270-026-04563-8

PMCPMC13642511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.