ArticleAnimal genetics2026
A Functional SNP in the Promoter Region of Ovine IDO2 Associated With Melatonin Levels via Affecting Transcription Activity by CLOCK.
Xunping Jiang, Shaxuan Chi, Xiaodong Wang, Mengya Chen, Zhuoying Tie, Huiguo Yang, Chaoli Wang, Guiqiong Liu
Abstract read
In one paragraphArticle in Animal genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
8 authors.
Xunping JiangKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.ORCID https://orcid.org/0000-0001-7822-1784 Shaxuan ChiKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Xiaodong WangKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Mengya ChenKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Zhuoying TieKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Huiguo YangInstitute of Animal Husbandry, Xinjiang Academy of Animal Sciences, Urumqi, People's Republic of China.
Guiqiong LiuKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.ORCID https://orcid.org/0000-0003-3688-5958 Funding
Biological breeding-national science and technology major project 2022ZD0401403China agriculture research system of MOF and MARA CARS-38Department of Science and Technology of Hubei Province HBZY2023B008Germplasm innovation project of prolificacy sheep in Xinjiang agricultural region 2023A02004-1Hubei livestock industrial technology system 2025HBSTX4-13Major program for breeding of high-performance meat sheep and goat in Hubei province 2023BAA029"Tianchi Talent" & "Tianshan Talent" distinguished experts programs 2023-2025
6 · The paper itselfAbstract
Sheep seasonal reproduction is regulated by photoperiod via melatonin. Indoleamine 2,3-dioxygenase 2 (IDO2), an enzyme involved in tryptophan metabolism through the kynurenine pathway and belonging to the IDO family, may contribute to melatonin homeostasis, but its role in reproductive seasonality remains unclear. In this study, genome-wide selection analyses combining Z(F
Indexed as
CLOCK ProteinsIndoleamine-Pyrrole 2,3,-DioxygenaseMelatoninPolymorphism, Single NucleotidePromoter Regions, GeneticSheep, DomesticAnimalsFemaleGenotypePhotoperiodSeasonsTranscription, GeneticCLOCK ProteinsIndoleamine-Pyrrole 2,3,-DioxygenaseMelatoninCLOCKIDOmelatoninreproduction rhythmsheepwhole‐genome sequencing
Identifiers
PMID42543215
PMCPMC13429496
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