Evidence map›Paper›PMID 42542798›Full record

ArticleCureus2026

Giant Cell Arteritis With Normal Inflammatory Markers and Progressive Visual Disturbance.

Saranya Kalyanasundaram Lakshmi, Usman Hassan, Pramodh Hettiarachchi, Deepti Kapur, Kumar Pulupula, Kausik Chatterjee

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saranya Kalyanasundaram LakshmiGeriatrics Department, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.
Usman HassanStroke Department, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.
Pramodh HettiarachchiStroke Department, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.
Deepti KapurRheumatology Department, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.
Kumar PulupulaRadiology Department, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.
Kausik ChatterjeeStroke Department, Countess of Chester Hospital NHS Foundation Trust, Chester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell arteritis (GCA) is a large vessel vasculitis classically presenting with headache, jaw claudication, visual disturbance, and raised inflammatory markers. However, atypical presentations occur, and a delay in recognition can lead to irreversible visual loss. We report a 75-year-old male with sequential ocular involvement in whom erythrocyte sedimentation rate and C-reactive protein remained within normal limits. Carotid/vertebrobasilar imaging showed atherosclerotic change without critical stenosis, and 18F-fluorodeoxyglucose PET demonstrated vertebral arterial uptake consistent with cranial GCA. High-dose corticosteroids were commenced with rheumatology input. Normal inflammatory indices do not exclude GCA. Clinicians should maintain a high index of suspicion when visual symptoms evolve and initiate treatment without delay where clinical probability is high.

Indexed as

gcagiant cell arteritisinflammatory markersmulti-modality imagingnormal inflammatory markersvasculitisvisual disturbance

Identifiers

PMID42542798
PMCPMC13428301

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.