ArticleSAGE open medicine2026
Validation of the Arabic version of the 23-item quality-of-life Kansas City Cardiomyopathy Questionnaire (KCCQ).
Article in SAGE open medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background and aim: The 23-item Kansas City Cardiomyopathy Questionnaire (KCCQ) is widely used to assess health-related quality of life (HRQoL) in HF patients covering key HF-related health status domains. This study validated the Arabic KCCQ version and looked into potential correlation between patients' HRQoL and their demographics/clinical characteristics, health literacy, medication adherence/knowledge. Methods: This was a multicenter validation study from Jordan including HF adult patients. Cronbach's alpha coefficient was employed to assess the scale internal consistency. Test-retest reliability evaluated stability of participants' responses overtime. Construct validity was examined through exploratory factor analysis (EFA), supported by Kaiser-Meyer-Olkin measure and Bartlett's sphericity test. Model fit was evaluated by confirmatory factor analysis (CFA). Associations between KCCQ scores and patient demographic/clinical characteristics, health literacy, medication adherence/knowledge were analyzed using linear regressions. Results: A total of 331 participants were recruited from two centers. KCCQ domains' scores ranged from mean±SD of 42.90±25.43 for symptom stability to 76.80±30.63 for social limitation. The total symptom, clinical summary and overall summary scores were 70.96±29.13, 74.67±25.67 and 70.67±25.70, respectively. The scale demonstrated excellent internal consistency (Cronbach's alpha=0.937). Test-retest analysis showed strong significant intraclass correlation coefficients and Pearson's correlation indicating good reliability. EFA and CFA supported data suitability for factor analysis and good model fit. The multivariate regression showed being married, performing exercise, being adherent to medication and taking fewer medications to significantly correlate to better HRQoL. Conclusion: The Arabic KCCQ version is a reliable, valid tool for HRQoL assessment among Arabic-speaking communities. Implementing interventions targeting sedentary HF patients not adherent to treatment regimen can improve HRQoL.
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