Evidence map›Paper›PMID 42542645›Full record

ArticleCureus2026

Complications of Otitis Media: Mastoiditis and an Intracranial Abscess Presenting as Behavioral Changes.

Tamer Yahya, Emily C Barbee, Ameer Kittaneh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tamer YahyaDepartment of Emergency Medicine, Mercy Health - St. Rita's Medical Center, Lima, USA.
Emily C BarbeeDepartment of Emergency Medicine, Mercy Health - St. Rita's Medical Center, Lima, USA.
Ameer KittanehDivision of Human Genetics and James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An intracranial abscess is a rare but life-threatening complication of otitis media (OM) and mastoiditis that requires rapid diagnosis and intervention. We present the case of a 43-year-old woman who presented with acute altered mental status and aggressive behavior following recent treatment for OM. Physical examination revealed a perforated, purulent right tympanic membrane, and neuroimaging confirmed bilateral mastoiditis and a right temporal lobe brain abscess with midline shift. Following treatment with broad-spectrum intravenous antibiotics, the patient underwent a successful craniotomy for abscess evacuation, a mastoidectomy, and tympanostomy tube placement. Postoperatively, her behavioral and neurological symptoms fully resolved, and she was discharged to complete a prolonged course of antimicrobial therapy. This case underscores the importance of maintaining a high index of suspicion for otogenic intracranial complications in patients presenting with acute behavioral changes, emphasizing that early, multidisciplinary surgical and medical management is essential to optimize patient outcomes.

Indexed as

abscessbehavioral changescomplicationsmastoiditisotitis

Identifiers

PMID42542645
PMCPMC13427670

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.