Evidence map›Paper›PMID 42542615›Full record

ArticleEClinicalMedicine2026

Standardised training for reducing peritoneal dialysis-related infection: a cluster randomised controlled study.

Josephine Sf Chow, Neil Boudville, Suetonia Green, Yeoungjee Cho, Gabor Mihala, Jessica Kasza, Ruth Campbell, Hayley Candler, Carmel M Hawley, Laura E Hickey and 31 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03816111 (A Pragmatic, Registry-based, International, Cluster-randomized Controlled Trial Examining the Use of TEACH-PD Training Modules for Incident PD Patients Versus Existing Practices on the Rate of PD-related Infections), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03816111 nacompletednot on this map

A Pragmatic, Registry-based, International, Cluster-randomized Controlled Trial Examining the Use of TEACH-PD Training Modules for Incident PD Patients Versus Existing Practices on the Rate of PD-related Infections

TypeinterventionalSponsorThe University of QueenslandRan2019 to 2025Enrolled1,462ConditionsKidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis, Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel InfectionArmsTEACH-PD Training Curriculum, Current standard PD training
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Josephine Sf ChowSouth Western Sydney Nursing and Midwifery Research Alliance, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.
Neil BoudvilleMedical School, University of Western Australia, Perth, Western Australia, Australia.
Suetonia GreenDunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Yeoungjee ChoDepartment of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Gabor MihalaAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Jessica KaszaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Ruth CampbellAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Hayley CandlerAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Carmel M HawleyDepartment of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Laura E HickeyAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Charani KiriwandeniyaAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Misa MatsuyamaAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Ramya MovvaAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Elaine M PascoeAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Donna M ReidlingerAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Andrea ValksAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Pushparaj VelayudhamAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Liza VergaraAustralasian Kidney Trials Network, Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Carolyn ArmstrongDepartment of Medicine, University of Otago, Christchurch, Christchurch, New Zealand.
Bernadette BuismanRenal Unit, Northern/Te Tai Tokerau, Whangārei, New Zealand.
Keri-Lu EquinoxDepartment of Renal Medicine, Cairns Hospital, Cairns, Queensland, Australia.
Ana E FigueiredoSchool of Nursing, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Trudi FugeLaunceston Hospital, Launceston, Tasmania, Australia.
Rachel HaseldenDepartment of Medicine, University of Otago, Christchurch, Christchurch, New Zealand.
Ashik HayatDepartment of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Kirsten HowardLeeder Centre for Health Policy, Economics and Data, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Martin HowellLeeder Centre for Health Policy, Economics and Data, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Allison JaureSydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Matthew D JoseSchool of Medicine, University of Tasmania, Hobart, Tasmania, Australia.
Anna LeeShoalhaven Hospital, Shoalhaven, New South Wales, Australia.
Susana San MiguelSouth Western Sydney Nursing and Midwifery Research Alliance, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.
Jo-Anne MoodieRenal Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Thu T NguyenRenal Unit, Te Toka Tumai Auckland, Auckland, New Zealand.
Walaa Wm SaweirsRenal Unit, Northern/Te Tai Tokerau, Whangārei, New Zealand.
Genevieve Z Steiner-LimNICM Health Research Institute, Western Sydney University Sydney, Penrith, New South Wales, Australia.
Melinda TomlinsDepartment of Nephrology, Hunter New England Local Health District, Wansey, New South Wales, Australia.
Megan UpjohnRenal Unit, Te Toka Tumai Auckland, Auckland, New Zealand.
David VossDepartment of Nephrology, Middlemore Hospital, Auckland, New Zealand.
Rachael C WalkerSchool of Nursing, Faculty of Health Medicine and Science, University of Auckland, Auckland, New Zealand.
David W JohnsonDepartment of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Collaborative Authors

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peritoneal dialysis is a widely used treatment for kidney failure; however, peritoneal dialysis-related infections (exit-site, tunnel infection, peritonitis) occur frequently. The effect of standardised nurse and patient training on peritoneal dialysis infections is uncertain. The aim of this study was to determine whether implementing an international guideline-based standardised training curriculum for nurse trainers and new peritoneal dialysis patients reduces the risk of peritoneal dialysis-related infections compared with existing local training practices. Methods: Targeted Education ApproaCH to improve Peritoneal Dialysis (TEACH-PD) was a pragmatic, investigator-initiated, cluster-randomised controlled trial conducted in Australia and New Zealand. Adult patients 18 years of age or older with kidney failure who required training for incident peritoneal dialysis treatment and who were able to provide written informed consent were eligible. Clusters were randomised 1:1 to either the standardised training curriculum or usual care. Participant data and infection outcomes were routinely collected in national patient registries. The primary outcome was time to first peritoneal dialysis-related infection (exit site infection, tunnel infection, or peritonitis). Secondary outcomes were the first of each individual infection type in the primary composite outcome, catheter removal, haemodialysis transfer, all-cause death and quality of life. This trial was registered with ClinicalTrials.gov, number NCT03816111. Findings: Between 22 July 2019 and 29 September 2023, 42 clusters were randomised: 21 to the standardised training group and 21 to the usual care group. Overall, 1462 incident peritoneal dialysis patients were included; 667 were assigned to the standardised training group and 795 to the usual care group. A peritoneal dialysis-related infection occurred in 296 of 667 patients in the standardised training group and 297 of 795 patients in the usual care group (sub-hazard ratio 1.230, 95% confidence interval [CI] 1.004-1.507, p = 0.0457). Secondary outcomes were similar in the two groups. Interpretation: Among patients commencing peritoneal dialysis, the use of a standardised training curriculum for nurses and patients based on the International Society for Peritoneal Dialysis guidelines increased peritoneal dialysis-related infection. Implementation-focused research is needed to identify which elements of training require standardisation and where individualisation is most beneficial to support safe, sustainable and patient-centred peritoneal dialysis care. Funding: The TEACH-PD trial is funded by MRFF Clinical Trials Activity: Rare Cancers, Rare Diseases and Unmet Need Grant Opportunity; National Health & Medical Research Council BEAT-CKD Program Grant; Health Research Council of New Zealand grant; Metro South Health Research Support Scheme Research Fund-Health System and Health Economics Project Grant; Queensland Health; South Western Sydney Research Small Grant Scheme; International Society for Peritoneal Dialysis; Translational Research Institute Australia; Amgen and Baxter Healthcare (Vantive).

Indexed as

Catheter-related infectionsCluster analysisCluster randomised controlled trialCompetency assessmentCost-effectivenessInfectionNurseNursingNursing educationPatient educationPeritoneal dialysisPeritonitisRandomised controlled trialsRegistryTreatment outcome

Identifiers

PMID42542615
PMCPMC13427580

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.