Evidence map›Paper›PMID 42541767›Full record

ArticleVeterinary surgery : VS2026

Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study.

Grigorios Maleas, Mahmoud Mageed, Kristyna Hargitaiova

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Article in Veterinary surgery : VS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Grigorios MaleasEquuria Orthopedics, Emstek, Germany.ORCID https://orcid.org/0000-0002-1774-6840
Mahmoud MageedEquuria Orthopedics, Emstek, Germany.ORCID https://orcid.org/0000-0003-2686-0407
Kristyna HargitaiovaCollege of Veterinary Medicine, Cornell University, Ithaca, USA.ORCID https://orcid.org/0009-0007-3020-7319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine short- and long-term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate-to-severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. STUDY

designRetrospective observational study. ANIMALS: A total of 21 client-owned Warmblood horses with DSB pathology unresponsive to conservative management.

methodsPreoperative diagnosis included lameness localization by diagnostic analgesia and magnetic resonance imaging (MRI) confirmation of DSB trabecular pathology. Horses underwent arthroscopic core decompression via the palmar recess of the distal interphalangeal joint followed by intraosseous BMAC injection. Outcomes were assessed clinically and by follow-up radiography and MRI.

resultsNo major intraoperative or postoperative complications occurred in any of the 21 operated horses. Nine horses met inclusion criteria for long-term follow-up, which included clinical, radiographic, and MRI assessments at 6 months and up to 18 months postoperatively. At 6 months, six of nine horses (67%) were sound and returned to training. MRI follow-up demonstrated reduced short tau inversion recovery (STIR) hyperintensity and increased T1-weighted signal within the DSB trabecular bone, consistent with a reduction in active trabecular bone pathology. Three horses remained lame with unchanged MRI findings. At 18 months, six horses remained sound, and three returned to their previous or intended performance levels. Radiographic remodeling of cyst-like lesions was evident in three cases.

conclusionCore decompression augmented with BMAC was well tolerated with no unexpected complications in this cohort. This approach allowed horses with advanced DSB trabecular pathology refractory to conservative therapy return to function. CLINICAL IMPACT: This combined surgical-orthobiologic approach may offer a viable therapeutic option for horses with advanced refractory navicular bone pathology.

Indexed as

Bone Marrow TransplantationDecompression, SurgicalHorse DiseasesSesamoid BonesAnimalsArthroscopyFemaleHorsesLameness, AnimalMagnetic Resonance ImagingMaleRetrospective StudiesTreatment Outcome

Identifiers

PMID42541767
PMCPMC13643678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.