Evidence map›Paper›PMID 42541647›Full record

Observational studyInternational journal of clinical oncology2026

Return to work after upper gastrointestinal cancer surgery: questionnaire-based observational study.

Tatsuma Sakaguchi, Takuya Fukushima, Nobuyuki Yamamoto, Satoshi Toshiyama, Shota Eguchi, Shuta Takaishi, Hanako Koda, Nozomi Matsushita, Takashi Harino, Yuki Hashimoto and 7 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tatsuma SakaguchiDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Takuya FukushimaFaculty of Rehabilitation, Kansai Medical University, Hirakata, Osaka, Japan.
Nobuyuki YamamotoDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Satoshi ToshiyamaDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Shota EguchiDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Shuta TakaishiDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Hanako KodaDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Nozomi MatsushitaDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Takashi HarinoDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Yuki HashimotoDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Masaya KotsukaDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Takuji SatoDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Hiromi MukaideDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Takuya SaitoDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Kentaro InoueDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Jiro NakanoFaculty of Rehabilitation, Kansai Medical University, Hirakata, Osaka, Japan.
Makoto YamasakiDepartment of Upper Gastrointestinal Surgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan. yamasaki.mak@kmu.ac.jp.ORCID http://orcid.org/0000-0003-4810-3343

Funding

Japan Society for the Promotion of Science 25K12041
6 · The paper itself

Abstract

backgroundReturn to work (RTW) is an important component of cancer survivorship. However, evidence on RTW after upper gastrointestinal cancer surgery remains limited.

methodsWe performed a questionnaire-based observational study between August 2023 and August 2025. Patients who underwent surgery with curative intent for upper gastrointestinal cancer, attended postoperative outpatient follow-up visits, and had been employed at the time of cancer diagnosis were eligible for this analysis.

resultsAmong 410 patients who completed the questionnaire, 207 had been employed at the time of cancer diagnosis. Of these 207 patients, 144 had returned to work (70%). Patients who returned to work were younger than those who did not (median age, 62.5 vs. 65.0 years; P = 0.013). In multivariable logistic regression analysis, older age was associated with a lower likelihood of RTW; however, this association was attenuated and no longer statistically significant after further adjustment for employment status (full-time or part-time worker). The cumulative probability of self-reported RTW was significantly higher in patients aged < 65 years than in those aged ≥ 65 years (P = 0.011). Approximately 85% of patients who ultimately returned to work had resumed work by 6 months after surgery.

conclusionsMost patients who ultimately returned to work did so within 6 months after surgery. RTW after upper gastrointestinal cancer surgery appears to be influenced by occupational and social circumstances; older age may serve as a proxy for these circumstances rather than an independent determinant of RTW, highlighting the potential value of individualized survivorship care and timely RTW support.

Indexed as

Gastrointestinal NeoplasmsReturn to WorkAgedFemaleHumansMaleMiddle AgedSurveys and QuestionnairesQuestionnaire studyReturn to workSurgerySurvivorshipUpper gastrointestinal cancer

Identifiers

PMID42541647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.