Evidence map›Paper›PMID 42541597›Full record

ArticleAngiogenesis2026

Functional definition of endothelial progenitors by PROCR and PDGFRA co-expression.

Cassandra Styke, Simranpreet Kaur, Seen-Ling Sim, Jilai Zhao, Chenhao Zhou, Ho Yi Wong, Jatin Patel, Edwige Roy, Mervyn C Yoder, Richard P Harvey and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angiogenesis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cassandra Styke *The University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
Simranpreet Kaur *Mater Research-The University of Queensland, Brisbane, QLD, 4101, Australia.
Seen-Ling SimThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
Jilai ZhaoThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
Chenhao ZhouThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
Ho Yi WongThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
Jatin PatelQueensland University of Technology, Brisbane, QLD, 4101, Australia.
Edwige RoyThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
Mervyn C YoderDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA, 15219, USA.
Richard P HarveyVictor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.
Abbas ShafieeThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia. a.shafiee@uq.edu.au.
Kiarash KhosrotehraniThe University of Queensland Frazer Institute, The University of Queensland, Brisbane, QLD, 4102, Australia. k.khosrotehrani@uq.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The functional and molecular definition of progenitors giving rise to blood vessel endothelium in vivo remains disputed. Upon investigating the overlap of seemingly divergent reports currently defining putative endothelial progenitor cells (EPCs) using single-cell RNA-sequencing and flow cytometry, Protein C Receptor (PROCR) and Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) largely overlapped with previously characterized murine aorta's CD34

Indexed as

Endothelial Progenitor CellsEndothelial Protein C ReceptorReceptor, Platelet-Derived Growth Factor alphaAnimalsAortaFemaleHumansMicePlacentaEndothelial Protein C ReceptorReceptor, Platelet-Derived Growth Factor alphaEndothelial cellsLineage tracingRefined endovascular progenitorsRegenerationVascularization

Identifiers

PMID42541597
PMCPMC13428779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.