Evidence map›Paper›PMID 42541546›Full record

ReviewPediatric radiology2026

Differentiating focal nodular hyperplasia from hepatic adenoma using a multimodality approach in children.

Alice Ashworth, Greg Chambers

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alice AshworthDepartment of Paediatric Radiology, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds, LS1 3EX, UK.
Greg ChambersDepartment of Paediatric Radiology, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds, LS1 3EX, UK. g.chambers@nhs.net.ORCID https://orcid.org/0000-0003-2000-3201

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiological characterisation of liver tumours in children aims to differentiate benign from malignant or potentially malignant lesions, and where possible, obviate the need for biopsy. This approach aims to reduce unnecessary morbidity and parental/patient anxiety and promotes judicious use of radiological and surgical resources. Focal nodular hyperplasia (FNH) and hepatic adenoma usually have a benign course but require tailored imaging follow-up and management due to their propensity to enlarge and/or mimic malignancy. In the case of hepatic adenoma, malignant transformation and tumour haemorrhage/rupture are the key concerns. This paper will discuss the clinical course of these two entities, their typical imaging findings on a range of modalities and how this impacts decision-making at the clinical level. The utility of hepatobiliary-specific MRI contrast agents will be discussed with reference to their key role in differentiating FNH from hepatic adenoma, whilst highlighting limitations and potential interpretation pitfalls.

Indexed as

AdolescentChildContrast mediaFocal nodular hyperplasiaLiver neoplasmsMagnetic resonance imaging

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.