ArticleArchives of insect biochemistry and physiology2026
Characterization and Seasonal Expression Profiling of a Takeout/Juvenile Hormone-Binding Protein-Family Gene Associated With Diapause in Eurygaster integriceps.
Article in Archives of insect biochemistry and physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Diapause in the Sunn pest, Eurygaster integriceps, is a key seasonal adaptation associated with migration, overwintering survival, and reproductive timing. However, the molecular components associated with this physiological state remain poorly characterized in this hemipteran pest. In this study, we identified and characterized a takeout-family transcript from E. integriceps (EiTO1; GenBank OP913374.1) and combined evolutionary, structural, and expression analyses to examine its association with seasonal physiological states. EiTO1 contained a 738-bp open reading frame encoding a 245-amino acid protein and was assigned to the juvenile hormone-binding protein (JHBP) superfamily based on conserved-domain analysis. Phylogenetic reconstruction recovered EiTO1 as sister to the Nilaparvata lugens-Bemisia tabaci clade; however, the low bootstrap support for this placement prevented confident inference of its closest evolutionary relationship. Structural comparison of the predicted EiTO1 model with experimentally resolved takeout/JHBP-family proteins indicated a conserved barrel-like fold and a corresponding internal cavity, consistent with structural features of this protein family. Quantitative PCR profiling revealed marked seasonal and tissue-specific variation in EiTO1 expression. In female whole-body samples, EiTO1 transcript abundance was low during spring field activity and in newly emerged adults sampled in June, reached its maximum during the refuge-associated phase in August (160-fold), and showed a secondary increase during the late-overwintering/premigration transition in March (21.5-fold). Tissue-resolved assays in females showed the highest expression in the head and intermediate expression in the fat body. Ovarian expression remained at or below the April baseline at most sampling points but showed a transient increase in August. Together, these findings identify EiTO1 as a takeout/JHBP-family gene whose expression is associated with seasonal physiological transitions in E. integriceps.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.