Evidence map›Paper›PMID 42541399›Full record

ArticleArchives of insect biochemistry and physiology2026

Valorization of Ficus carica Pruning Residues as Selective Botanical Insecticides: Optimized Furanocoumarin Extraction, Efficacy Against Neotropical Stink Bugs, and Mechanistic Insights via Molecular Docking.

Thais A Almeida, Arley R Páez, Lara T M Costa, Guy Smagghe, Yara M Cardoso, Letícia M Faria, Eugênio E Oliveira, João Paulo V Leite

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of insect biochemistry and physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thais A AlmeidaDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.
Arley R PáezDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0004-0471-4622
Lara T M CostaDepartment of Entomology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.
Guy SmaggheInstitute of Entomology, Guizhou University, Guiyang, Guizhou, China.ORCID https://orcid.org/0000-0001-8334-3313
Yara M CardosoDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.
Letícia M FariaDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.
Eugênio E OliveiraDepartment of Entomology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0003-1174-6564
João Paulo V LeiteDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, University Campus, Viçosa, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-3747-4424

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302871/2022-5Conselho Nacional de Desenvolvimento Científico e Tecnológico 309890/2022-5Conselho Nacional de Desenvolvimento Científico e Tecnológico 408598/2023-9Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.947511/2024-00Embrapa café 155/2024Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-05316-23Rede de Pesquisa em Biodiversidade e Sustentabilidaded 406399/2022-0
6 · The paper itself

Abstract

The Neotropical stink bugs Euschistus heros and Diceraeus melacanthus are major pests of soybean and maize in South America, yet current chemical control strategies face widespread resistance, highlighting the urgent need for sustainable alternatives. This study investigates Ficus carica pruning residues as a source of selective botanical insecticides, integrating optimized extraction, phytochemical profiling, bioassays, and molecular modeling. Eight extracts were prepared under varying solvent, temperature, and acidity conditions, and analyzed for total phenolic content (TPC) and the key furanocoumarins psoralen and bergapten. Acidification enhanced overall mass yields, while mild ethanol extraction at room temperature selectively maximized furanocoumarin recovery, yielding psoralen concentrations up to 14.83 mg g

Indexed as

FicusFurocoumarinsInsecticidesPlant ExtractsTetranychidaeAnimalsInsect ControlMolecular Docking SimulationFurocoumarinsInsecticidesPlant Extractsagricultural residuesbergapteninsecticidal activityMoraceaePentatomidaepsoralentarget selectivity

Identifiers

PMID42541399
PMCPMC13428401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.