ArticleResuscitation plus2026
Dispatcher-assisted AED use in single-rescuer cardiac arrest: study protocol for a randomized simulation study comparing standard and optimized dispatcher-assisted CPR instructions.
Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07520877 (Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction in a Single-rescuer Cardiac Arrest Scenario - a Randomized-controlled Simulation Study), which is not on this map. Not yet cited in PubMed.
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Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction in a Single-rescuer Cardiac Arrest Scenario - a Randomized-controlled Simulation Study
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5 authors.
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Abstract
Background: Although automated external defibrillators (AEDs) improve outcomes in shockable rhythms, their use introduces interruptions in chest compressions. In single-rescuer scenarios, AED retrieval and application may further increase no-flow time. The effect of dispatcher instruction strategy on these interruptions remains unclear. This study aims to evaluate whether AED-optimized dispatcher-assisted CPR (DACPR) instructions reduce no-flow time compared with standard instructions in a simulated single-rescuer OHCA setting. Methods: This prospective, randomized, controlled, parallel-group simulation trial will include adult laypersons and healthcare professionals. Participants will be allocated in a 1:1 ratio to either standard or AED-optimized DACPR instruction groups. All scenarios will be conducted in a controlled simulation environment with standardized AED accessibility (≤1 min retrieval distance) to isolate the effect of dispatcher communication on CPR performance. The primary outcome will be total no-flow time. Secondary outcomes include chest compression fraction, time to first compression, time to first shock, peri-shock pauses, and CPR quality metrics. Discussion: This study investigates dispatcher instruction as a modifiable determinant of CPR interruption during AED use in single-rescuer scenarios. Findings will provide mechanistic insight into how communication strategies influence CPR quality under controlled conditions and may inform refinement of DACPR protocols. Ethics and dissemination: The study protocol was approved by the Institutional Ethics Committee of the University of Pécs (PTE/87175-1/2025). Written informed consent will be obtained. Results will be disseminated via peer-reviewed publication and scientific conferences. Trial registration: ClinicalTrials.gov: NCT07520877, prospectively registered on 8 April 2026.
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