Evidence map›Paper›PMID 42541291›Full record

ArticleBioactive materials2026

Study on the repair effect of photothermal hydrogel with controllable adhesiveness regulated by melanin and magnesium ions on diabetic wounds.

Lan Guo, Keying Wu, Ruxin Wang, Yadong Xue, Yanru Diao, Junfeng Ai, Qingqing Bi, Baoqin Han, Xubo Wang, Jing Chang

Abstract read
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In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lan GuoCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.
Keying WuCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.
Ruxin WangCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.
Yadong XueKey Laboratory of Aquacultural Biotechnology (Ningbo University), Ministry of Education, Ningbo, 315211, China.
Yanru DiaoCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.
Junfeng AiCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.
Qingqing BiDepartment of Clinical Laboratory, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, China.
Baoqin HanCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.
Xubo WangKey Laboratory of Aquacultural Biotechnology (Ningbo University), Ministry of Education, Ningbo, 315211, China.
Jing ChangCollege of Marine Life Science, Ocean University of China, Qingdao, 266003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic non-healing wounds, characterized by prolonged disease duration and low compromised reparative potential, not only cause patients to suffer from persistent physical pain and impaired daily living ability, but also are prone to inducing severe complications such as infection and amputation, posing a serious threat to patients' health and quality of life. In this study, a melanin derivative (M-HPCS) with excellent photothermal properties was successfully prepared through the condensation reaction between natural squid melanin and a chitosan derivative (HPCS). Subsequently, by virtue of charge interaction, M-HPCS was assembled with a hyaluronic acid derivative (HA-PEG) to construct a photothermal hydrogel (M-HPCS/HA-PEG) with controllable adhesion performance. This hydrogel could further enhance its own adhesion capacity by chelating magnesium ions, making it suitable for the repair and treatment of non-healing wounds. The results demonstrated that, relying on the dual regulatory effect of sepia melanin and Mg

Indexed as

Chronic non-healing woundsControllable adhesionMagnesium ion complexationPhotothermal hydrogelSquid melanin

Identifiers

PMID42541291
PMCPMC13427411

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.