Evidence map›Paper›PMID 42541232›Full record

ArticleO&G open2026

Lysis of Vulvar Adhesions and Sexual Function in Vulvar Lichen Sclerosus.

Jill M Krapf, Esha Ghosalkar, Amelia Goldstein, Gracie Nootz, Sylvia Lorenzini, Rosa Hahn, Chailee Moss, Andrew T Goldstein

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in O&G open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jill M KrapfCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Esha GhosalkarCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Amelia GoldsteinCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Gracie NootzCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Sylvia LorenziniCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Rosa HahnCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Chailee MossCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.
Andrew T GoldsteinCenter for Vulvovaginal Disorders Florida, Tampa, Florida; Case Western Reserve University School of Medicine, Cleveland, Ohio; Centers for Vulvovaginal Disorders, Washington, DC; and Centers for Vulvovaginal Disorders, New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of surgical interventions, specifically surgical correction of introital stenosis and clitoral phimosis in a procedure called lysis of vulvar adhesions, on sexual function, sexual distress, and overall patient satisfaction in individuals with vulvar lichen sclerosus.

methodsA pre-post intervention mixed-methods cohort study was conducted on patients at three urban medical centers treating vulvar disorders from December 2013 to January 2025. Participants completed preoperative and postoperative assessments, including the Female Sexual Function Index, Female Sexual Distress Scale, and descriptive response questions regarding surgical outcomes. Statistical analysis was conducted with descriptive statistics and paired-sample

resultsA total of 86 patients (median age 48.2±14.0 years) participated in the study, completing both preoperative and postoperative surveys. Female Sexual Distress Scale scores decreased from 30.2±11.84 preoperatively to 16.6±13.40 postoperatively (

conclusionPatients with vulvar lichen sclerosus who undergo surgical management of vulvar adhesions report significant improvements in sexual function and distress with high satisfaction rates. Although a small subset of patients required revision surgeries, the overall positive outcomes support the procedure as an effective intervention for symptomatic scarring in the setting of vulvar lichen sclerosus. These results emphasize the need for providing adequate preoperative counseling and setting realistic expectations of outcomes to optimize long-term success and patient satisfaction.

Identifiers

PMID42541232
PMCPMC13427383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.