ArticleCureus2026
Lateralization of Bilateral Temporal Lobe Epilepsy After Vagus Nerve Stimulation Surgery.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Drug-resistant bilateral temporal lobe epilepsy is associated with poor outcomes following resective surgery because of the lack of a clearly lateralized focus. Vagus nerve stimulation (VNS) provides symptomatic benefit, but its potential role in facilitating surgical candidacy remains underrecognized. We describe a 32-year-old woman who developed drug-resistant bilateral temporal lobe epilepsy after herpes simplex virus encephalitis at age 13. Seizures included dialeptic, hypermotor, and generalized tonic-clonic events without consistent lateralizing features. Scalp electroencephalography showed bilateral independent temporal discharges, and magnetic resonance imaging revealed bilateral mesial temporal atrophy. At age 19, she underwent VNS implantation. Subsequent electroencephalography demonstrated progressive lateralization of interictal and ictal discharges to the right temporal lobe. At age 29, she underwent right anterior temporal lobectomy (ATL), resulting in Engel Class I seizure freedom. This case illustrates the potential of VNS not only as a palliative therapy but also as an inducer of lateralization of discharges, thereby enabling patients to undergo curative resective surgery.
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