ArticleGynecology and minimally invasive therapy
A Randomized Clinical Trial Comparing the Effect of Rectal Misoprostol with Intramyometrial Vasopressin on Blood Loss during Laparoscopic Myomectomy.
Article in Gynecology and minimally invasive therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Objectives: This study aimed to compare the efficacy of rectal misoprostol combined with intramyometrial normal saline versus intramyometrial vasopressin in reducing blood loss during laparoscopic myomectomy. Materials and Methods: This was a randomized, double blind, controlled trial (CTRI/2023/05/053204). A total of 70 women scheduled for laparoscopic myomectomy were enrolled and equally randomized into two groups: Group I (received rectal misoprostol 400 µg 1 h before surgery) and Group II (received intramyometrial vasopressin 20 IU in 200 ml NS dilution). Final analysis was conducted on 64 patients due to missing data (4 in Group I and 2 in Group II). The primary outcome was intraoperative blood loss. Results: Baseline clinical characteristics were similar between the groups. Intraoperative blood loss was significantly higher in the misoprostol Group I compared to the vasopressin Group II (320.9 ± 131.9 mL vs. 246 ± 119.3 mL; Conclusion: Vasopressin was more effective than misoprostol in reducing intraoperative blood loss and postoperative hemoglobin drop during laparoscopic myomectomy.
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